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    CG11841 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43430, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG11841provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0039628
    Locus tag
    Dmel_CG11841
    See related
    AllianceGenome:FB:FBgn0039628
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0140519.18; anon-WO0140519.6; BcDNA:GH26583; Dmel\CG11841; SP45
    Summary
    Predicted to enable serine-type endopeptidase activity. Predicted to be involved in innate immune response and proteolysis. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG11841 in Genome Data Viewer
    Location:
    98F6-98F6; 3-97 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (29051056..29052267)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (24876778..24877989)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Protein C kinase 98E Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene antisense RNA:CR46107 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The endogenous siRNA pathway in Drosophila impacts stress resistance and lifespan by regulating metabolic homeostasis. Lim DH, et al. FEBS Lett, 2011 Oct 3. PMID 21889502
    2. A kappaB sequence code for pathway-specific innate immune responses. Busse MS, et al. EMBO J, 2007 Aug 22. PMID 17660749, Free PMC Article
    3. A genome-wide analysis of immune responses in Drosophila. Irving P, et al. Proc Natl Acad Sci U S A, 2001 Dec 18. PMID 11742098, Free PMC Article
    4. Parasite-specific immune response in adult Drosophila melanogaster: a genomic study. Roxström-Lindquist K, et al. EMBO Rep, 2004 Feb. PMID 14749722, Free PMC Article
    5. The tobacco phosphatidylethanolamine-binding protein NtFT4 increases the lifespan of Drosophila melanogaster by interacting with the proteostasis network. Känel P, et al. Aging (Albany NY), 2022 Apr 8. PMID 35396341, Free PMC Article

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables serine-type endopeptidase activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proteolysis ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG11841-PA
    NP_651661.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      29051056..29052267
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143404.2 → NP_651661.1  uncharacterized protein Dmel_CG11841 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651661.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3DNL2, Q9VAQ4
      Related
      FBpp0084730
      Conserved Domains (2) summary
      smart00020
      Location:72 → 310
      Tryp_SPc; Trypsin-like serine protease
      cd00190
      Location:72 → 311
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8IH38 Q8IH38
    Q9VAQ4 Q9VAQ4

    Gene LinkOut

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