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    ORY Occludin-Related Y [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3355174, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ORYprovided by FlyBase
    Official Full Name
    Occludin-Related Yprovided by FlyBase
    Primary source
    FLYBASE:FBgn0046323
    Locus tag
    Dmel_CG40446
    See related
    AllianceGenome:FB:FBgn0046323
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG40446; Dmel\CG40446; FBgn0046323; ory; Ory
    Summary
    Predicted to be active in cytoskeleton. Is expressed in adult head and spermatozoon. Human ortholog(s) of this gene implicated in spermatogenic failure 49. Orthologous to human CFAP58 (cilia and flagella associated protein 58). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See ORY in Genome Data Viewer
    Location:
    chromosome: Y
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) Y NC_024512.1 (3561745..3618339)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) YHet NW_001848860.1 (229033..271450)

    Chromosome Y - NC_024512.1Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene Protein phosphatase 1, Y-linked 2 Neighboring gene Coiled-Coils Y

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Ancient evolutionary signals of protein-coding sequences allow the discovery of new genes in the Drosophila melanogaster genome. Casimiro-Soriguer CS, et al. BMC Genomics, 2020 Mar 5. PMID 32138644, Free PMC Article
    2. Extensive introgression of mitochondrial DNA relative to nuclear genes in the Drosophila yakuba species group. Bachtrog D, et al. Evolution, 2006 Feb. PMID 16610321
    3. Surprising differences in the variability of Y chromosomes in African and cosmopolitan populations of Drosophila melanogaster. Larracuente AM, et al. Genetics, 2013 Jan. PMID 23086221, Free PMC Article
    4. Identification of five new genes on the Y chromosome of Drosophila melanogaster. Carvalho AB, et al. Proc Natl Acad Sci U S A, 2001 Nov 6. PMID 11687639, Free PMC Article
    5. Polymorphic Y chromosomes harbor cryptic variation with manifold functional consequences. Lemos B, et al. Science, 2008 Jan 4. PMID 18174442

    See all (36) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    mobile_element

    • Loc: 3606948-3608001 mobile_element_type = transposon:1360{}6489

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Occludin-Related Y
    Names
    CG40446-PD
    ORY-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_024512.1 Reference assembly

      Range
      3561745..3618339
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001015498.5 → NP_001015498.5  Occludin-Related Y [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5LJN3, Q95V49
      Conserved Domains (2) summary
      COG1196
      Location:182 → 488
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:363 → 686
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q281X4 Q281X4
    Q5LJN3 Q5LJN3
    Q95V49 Q95V49

    Gene LinkOut

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