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    COX7B Cytochrome c oxidase subunit 7B [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 50266, updated on 27-Dec-2024

    Summary

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    Official Symbol
    COX7Bprovided by FlyBase
    Official Full Name
    Cytochrome c oxidase subunit 7Bprovided by FlyBase
    Primary source
    FLYBASE:FBgn0040793
    Locus tag
    Dmel_CG7630
    See related
    AllianceGenome:FB:FBgn0040793
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Posey153; anon-EST:Posey228; BcDNA:RH19679; CG7630; Dmel\CG7630
    Summary
    Involved in mitochondrial electron transport, cytochrome c to oxygen. Located in mitochondrial inner membrane. Part of respiratory chain complex IV. Is expressed in several structures, including adult head; anterior endoderm; anterior endoderm anlage; dorsal pharyngeal muscle cell; and embryonic/larval midgut primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See COX7B in Genome Data Viewer
    Location:
    74B3-74B3; 3-45 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (17425477..17426282)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (17418577..17419382)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene bloated tubules Neighboring gene long non-coding RNA:noe Neighboring gene Secretory 3 Neighboring gene RNA polymerase III subunit G Neighboring gene Golgin, RAB6 interacting

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cell-type-specific, multicolor labeling of endogenous proteins with split fluorescent protein tags in Drosophila. Kamiyama R, et al. Proc Natl Acad Sci U S A, 2021 Jun 8. PMID 34074768, Free PMC Article
    2. CG7630 is the Drosophila melanogaster homolog of the cytochrome c oxidase subunit COX7B. Brischigliaro M, et al. EMBO Rep, 2022 Aug 3. PMID 35699132, Free PMC Article
    3. Proteomic mapping in live Drosophila tissues using an engineered ascorbate peroxidase. Chen CL, et al. Proc Natl Acad Sci U S A, 2015 Sep 29. PMID 26362788, Free PMC Article
    4. Extensive translation of small Open Reading Frames revealed by Poly-Ribo-Seq. Aspden JL, et al. Elife, 2014 Aug 21. PMID 25144939, Free PMC Article
    5. Genome-wide analysis reveals an unexpected function for the Drosophila splicing factor U2AF50 in the nuclear export of intronless mRNAs. Blanchette M, et al. Mol Cell, 2004 Jun 18. PMID 15200955

    See all (32) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, cytochrome c to oxygen IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of respiratory chain complex IV IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of respiratory chain complex IV IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cytochrome c oxidase subunit 7B
    Names
    CG7630-PA
    COX7B-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      17425477..17426282
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_144156.4 → NP_652413.1  cytochrome c oxidase subunit 7B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_652413.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VVG5
      Related
      FBpp0074979
      Conserved Domains (1) summary
      pfam16020
      Location:35 → 83
      Deltameth_res; Deltamethrin resistance
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VVG5 Q9VVG5

    Gene LinkOut

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