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    CG30178 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246501, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CG30178provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050178
    Locus tag
    Dmel_CG30178
    See related
    AllianceGenome:FB:FBgn0050178
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG17263; Dmel\CG30178
    Summary
    Predicted to enable transcription coregulator activity. Predicted to be active in Z disc and nucleus. Orthologous to human FHL2 (four and a half LIM domains 2) and FHL5 (four and a half LIM domains 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG30178 in Genome Data Viewer
    Location:
    60A16-60A16; 2-105 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (23986615..23987308)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (19874138..19874831)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Protein phosphatase 1 regulatory subunit 15 Neighboring gene Sox box protein 14 Neighboring gene Peptidylglycine-alpha-hydroxylating monooxygenase Neighboring gene PAS kinase Neighboring gene uncharacterized protein Neighboring gene mir-1009 stem loop

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PHM is required for normal developmental transitions and for biosynthesis of secretory peptides in Drosophila. Jiang N, et al. Dev Biol, 2000 Oct 1. PMID 10993678
    2. The Drosophila basic helix-loop-helix protein DIMMED directly activates PHM, a gene encoding a neuropeptide-amidating enzyme. Park D, et al. Mol Cell Biol, 2008 Jan. PMID 17967878, Free PMC Article
    3. The anaphase promoting complex/cyclosome is required during development for modified cell cycles. Kashevsky H, et al. Proc Natl Acad Sci U S A, 2002 Aug 20. PMID 12169670, Free PMC Article
    4. The Roles of the LIM Domain Proteins in Drosophila Cardiac and Hematopoietic Morphogenesis. She M, et al. Front Cardiovasc Med, 2021. PMID 33681304, Free PMC Article
    5. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Z disc IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG30178-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      23986615..23987308
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_166645.3 → NP_726395.1  uncharacterized protein Dmel_CG30178 [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      B5X523, Q8MLQ2
      Related
      FBpp0072068
      Conserved Domains (2) summary
      cd08368
      Location:65 → 116
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      cl02475
      Location:124 → 171
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MLQ2 Q8MLQ2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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