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    CG8613 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36593, updated on 27-Dec-2024

    Summary

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    Official Symbol
    CG8613provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033924
    Locus tag
    Dmel_CG8613
    See related
    AllianceGenome:FB:FBgn0033924
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG8613
    Summary
    Predicted to be involved in carbohydrate metabolic process. Predicted to be located in mitochondrion. Is expressed in adult head. Orthologous to human SPATA20 (spermatogenesis associated 20). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG8613 in Genome Data Viewer
    Location:
    50F6-50F6; 2-70 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (14352231..14355674)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (10239736..10243179)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene tejas Neighboring gene Shroom Neighboring gene uncharacterized protein Neighboring gene Activity-regulated cytoskeleton associated protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Environmental chemical mediated male reproductive toxicity: Drosophila melanogaster as an alternate animal model. Tiwari AK, et al. Theriogenology, 2011 Jul 15. PMID 21356551
    2. Overexpression of myocilin in the Drosophila eye activates the unfolded protein response: implications for glaucoma. Carbone MA, et al. PLoS One, 2009. PMID 19148291, Free PMC Article
    3. Genome-wide identification and characterization of tissue-specific RNA editing events in D. melanogaster and their potential role in regulating alternative splicing. Mazloomian A, et al. RNA Biol, 2015. PMID 26512413, Free PMC Article
    4. Latitudinal clines in gene expression and cis-regulatory element variation in Drosophila melanogaster. Juneja P, et al. BMC Genomics, 2016 Nov 28. PMID 27894253, Free PMC Article
    5. Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. Blanco E, et al. BMC Dev Biol, 2010 Sep 2. PMID 20813047, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG8613-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      14352231..14355674
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137109.3 → NP_610953.1  uncharacterized protein Dmel_CG8613 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610953.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q5BIA9
      Related
      FBpp0086674
      Conserved Domains (3) summary
      COG1331
      Location:77 → 800
      YyaL; Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains [General function prediction only]
      pfam03190
      Location:77 → 238
      Thioredox_DsbH; Protein of unknown function, DUF255
      cl23840
      Location:271 → 440
      AGE; AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5BIA9 Q5BIA9
    Q95SN1 Q95SN1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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