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    CG30392 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246587, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG30392provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050392
    Locus tag
    Dmel_CG30392
    See related
    AllianceGenome:FB:FBgn0050392
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0153538.80; CG10509; Dmel\CG30392
    Summary
    Predicted to enable ceramide 1-phosphate binding activity and ceramide 1-phosphate transfer activity. Predicted to be involved in ceramide transport and intermembrane lipid transfer. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in adult head. Orthologous to several human genes including CPTP (ceramide-1-phosphate transfer protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG30392 in Genome Data Viewer
    Location:
    57D8-57D8; 2-94 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (21290914..21292181, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (17178419..17179686, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Major Facilitator Superfamily Transporter 16 Neighboring gene uncharacterized protein Neighboring gene SAGA-associated factor 29kDa Neighboring gene Ribosomal protein L29 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sec6 mutations and the Drosophila exocyst complex. Murthy M, et al. J Cell Sci, 2005 Mar 15. PMID 15728258
    2. Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling. Yin J, et al. Nat Commun, 2021 Apr 23. PMID 33893307, Free PMC Article
    3. Variation in the response to exercise stimulation in Drosophila: marathon runner versus sprinter genotypes. Riddle NC. J Exp Biol, 2020 Sep 21. PMID 32737212
    4. Somatic, germline and sex hierarchy regulated gene expression during Drosophila metamorphosis. Lebo MS, et al. BMC Genomics, 2009 Feb 13. PMID 19216785, Free PMC Article
    5. Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. Blanco E, et al. BMC Dev Biol, 2010 Sep 2. PMID 20813047, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ceramide 1-phosphate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ceramide 1-phosphate transfer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lipid transfer activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in ceramide transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intermembrane lipid transfer IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intermembrane lipid transfer IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG30392-PA
    CG30392-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      21290914..21292181 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299743.1 → NP_001286672.1  uncharacterized protein Dmel_CG30392, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286672.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MLW4, Q8T0V0
      Conserved Domains (1) summary
      pfam08718
      Location:42 → 186
      GLTP; Glycolipid transfer protein (GLTP)

    2. NM_137728.3 → NP_611572.2  uncharacterized protein Dmel_CG30392, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611572.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MLW4, Q8T0V0
      Related
      FBpp0071544
      Conserved Domains (1) summary
      pfam08718
      Location:42 → 186
      GLTP; Glycolipid transfer protein (GLTP)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8MLW4 Q8MLW4
    Q8T0V0 Q8T0V0

    Gene LinkOut

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