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    CG31145 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42784, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG31145provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051145
    Locus tag
    Dmel_CG31145
    See related
    AllianceGenome:FB:FBgn0051145
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10187; CG13820; CG13821; Dmel\CG31145
    Summary
    Predicted to enable protein serine/threonine kinase activity. Located in Golgi apparatus and extracellular region. Is expressed in several structures, including embryonic/larval midgut primordium; gland; gut section; midline glial cell; and nephrocyte. Human ortholog(s) of this gene implicated in amelogenesis imperfecta and amelogenesis imperfecta type 1G. Orthologous to several human genes including FAM20C (FAM20C golgi associated secretory pathway kinase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG31145 in Genome Data Viewer
    Location:
    95A4-95A7; 3-80 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (23605751..23669659, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19431473..19495381, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene transfer RNA:Leucine-CAA 2-3 Neighboring gene uncharacterized protein Neighboring gene Gamma-interferon-inducible lysosomal thiol reductase 3 Neighboring gene Gamma-interferon-inducible lysosomal thiol reductase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Quantitative genomics of locomotor behavior in Drosophila melanogaster. Jordan KW, et al. Genome Biol, 2007. PMID 17708775, Free PMC Article
    2. The Raine syndrome protein FAM20C is a Golgi kinase that phosphorylates bio-mineralization proteins. Ishikawa HO, et al. PLoS One, 2012. PMID 22900076, Free PMC Article
    3. Identification of a micropeptide and multiple secondary cell genes that modulate Drosophila male reproductive success. Immarigeon C, et al. Proc Natl Acad Sci U S A, 2021 Apr 13. PMID 33876742, Free PMC Article
    4. Sex Differences in Drosophila Somatic Gene Expression: Variation and Regulation by doublesex. Arbeitman MN, et al. G3 (Bethesda), 2016 Jul 7. PMID 27172187, Free PMC Article
    5. The Hox proteins Ubx and AbdA collaborate with the transcription pausing factor M1BP to regulate gene transcription. Zouaz A, et al. EMBO J, 2017 Oct 2. PMID 28871058, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables protein kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31145-PA
    CG31145-PB
    CG31145-PC
    CG31145-PD
    CG31145-PF
    CG31145-PG
    NP_001138101.1
    NP_001138102.1
    NP_001138103.2
    NP_001356923.1
    NP_732884.2
    NP_788724.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      23605751..23669659 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001369999.1 → NP_001356923.1  uncharacterized protein Dmel_CG31145, isoform G [Drosophila melanogaster]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4D6K5D6
      Conserved Domains (1) summary
      pfam06702
      Location:755 → 971
      Fam20C; Golgi casein kinase, C-terminal, Fam20

    2. NM_001144629.3 → NP_001138101.1  uncharacterized protein Dmel_CG31145, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138101.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4VCL2
      Conserved Domains (1) summary
      pfam06702
      Location:756 → 966
      Fam20C; Golgi casein kinase, C-terminal, Fam20

    3. NM_001144631.2 → NP_001138103.2  uncharacterized protein Dmel_CG31145, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138103.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4VCL2, B7Z0P4, B7Z0P6, C1C534, Q9VCK5
      Conserved Domains (1) summary
      pfam06702
      Location:304 → 514
      Fam20C; Golgi casein kinase, C-terminal, Fam20

    4. NM_170079.4 → NP_732884.2  uncharacterized protein Dmel_CG31145, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732884.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4VCL2, B7Z0P4, B7Z0P6, C1C534, Q9VCK5
      Related
      FBpp0083870
      Conserved Domains (1) summary
      pfam06702
      Location:304 → 514
      Fam20C; Golgi casein kinase, C-terminal, Fam20

    5. NM_176547.3 → NP_788724.1  uncharacterized protein Dmel_CG31145, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788724.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4VCL2, B7Z0P4, B7Z0P6, C1C534, Q9VCK5
      Related
      FBpp0083871
      Conserved Domains (1) summary
      pfam06702
      Location:304 → 514
      Fam20C; Golgi casein kinase, C-terminal, Fam20

    6. NM_001144630.2 → NP_001138102.1  uncharacterized protein Dmel_CG31145, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001138102.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4VCL2
      Conserved Domains (1) summary
      pfam06702
      Location:756 → 914
      Fam20C; Golgi casein kinase, C-terminal, Fam20
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A4D6K5D6 A0A4D6K5D6
    A4VCL2.2 A4VCL2

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