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    ADARB2-AS1 ADARB2 antisense RNA 1 [ Homo sapiens (human) ]

    Gene ID: 642394, updated on 10-Dec-2024

    Summary

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    Official Symbol
    ADARB2-AS1provided by HGNC
    Official Full Name
    ADARB2 antisense RNA 1provided by HGNC
    Primary source
    HGNC:HGNC:23299
    See related
    Ensembl:ENSG00000205696 AllianceGenome:HGNC:23299
    Gene type
    ncRNA
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    C10orf109; NCRNA00168
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See ADARB2-AS1 in Genome Data Viewer
    Location:
    10p15.3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (1526630..1557008)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (1526144..1554753)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (1568825..1599203)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene adenosine deaminase RNA specific B2 (inactive) Neighboring gene uncharacterized LOC105376342 Neighboring gene Sharpr-MPRA regulatory region 10920 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1421674-1422378 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1422379-1423081 Neighboring gene NANOG hESC enhancer GRCh37_chr10:1423311-1423822 Neighboring gene uncharacterized LOC124902364 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1449419-1450003 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr10:1451683-1452882 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1476825-1477620 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1477621-1478414 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:1501805-1503004 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1507617-1508326 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1516725-1517244 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1517245-1517763 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2902 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:1531466-1531632 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr10:1541598-1542797 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1564309-1564810 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1571713-1572712 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr10:1576761-1577960 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1594399-1594926 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1601202-1601702 Neighboring gene Sharpr-MPRA regulatory region 9114 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1644395-1644901 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1651053-1651582 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1651583-1652110 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:1652312-1652473 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1669763-1670264 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1670265-1670764 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1701309-1701862 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:1701863-1702414 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1704841-1705340 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1712437-1712938 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1712939-1713438 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2903 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1721606-1722106 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1722107-1722607 Neighboring gene ReSE screen-validated silencer GRCh37_chr10:1737450-1737614 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2904 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:1779051-1779647 Neighboring gene uncharacterized LOC105376345 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:1789244-1790443 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr10:1816736-1817445 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr10:1980919-1982118 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr10:1984230-1985429 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr10:2008580-2009779 Neighboring gene uncharacterized LOC105376346

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

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    Related articles in PubMed

    1. Linc-ing Circulating Long Non-coding RNAs to the Diagnosis and Malignant Prediction of Intraductal Papillary Mucinous Neoplasms of the Pancreas. Permuth JB, et al. Sci Rep, 2017 Sep 5. PMID 28874676, Free PMC Article
    2. The sequence of the human genome. Venter JC, et al. Science, 2001 Feb 16. PMID 11181995
    3. Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family. Li X, et al. Mol Cell Proteomics, 2016 Sep. PMID 27432908, Free PMC Article
    4. High-throughput analyses of hnRNP H1 dissects its multi-functional aspect. Uren PJ, et al. RNA Biol, 2016. PMID 26760575, Free PMC Article
    5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Phenotypes

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    Review eQTL and phenotype association data in this region using PheGenI

    Variation

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    See variants in ClinVar

    See studies and variants in dbVar

    See Variation Viewer (GRCh37.p13)

    See Variation Viewer (GRCh38)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Other Names

    • ADARB2 antisense RNA 1 (non-protein coding)

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_033387.2 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AF086274, DA335457
      Related
      ENST00000421697.2

    2. NR_152792.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      DA335457
      Related
      ENST00000754243.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      1526630..1557008
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      1526144..1554753
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001098830.1: Suppressed sequence

      Description
      NM_001098830.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A8MUL3.2 GenPept UniProtKB/Swiss-Prot:A8MUL3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Chemical Information
    Molecular Biology Databases
    Research Materials