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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_144633.3 → NP_653234.2 voltage-gated delayed rectifier potassium channel KCNH8
Status: REVIEWED
- Source sequence(s)
-
AC015542, AC061958, AC099538, AC116098, AC135452, AC138315
- Consensus CDS
-
CCDS2632.1
- UniProtKB/Swiss-Prot
- B7Z2I7, Q59GQ6, Q96L42
- Related
- ENSP00000328813.2, ENST00000328405.7
- Conserved Domains (7) summary
-
- COG0664
Location:548 → 685
- Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
- cd00038
Location:551 → 662
- CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
- cd00130
Location:42 → 133
- PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
- pfam00520
Location:239 → 481
- Ion_trans; Ion transport protein
- pfam06757
Location:848 → 899
- Ins_allergen_rp; Insect allergen related repeat, nitrile-specifier detoxification
- pfam07885
Location:421 → 475
- Ion_trans_2; Ion channel
- pfam13426
Location:29 → 135
- PAS_9; PAS domain