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    grs1 glycine--tRNA (Gly) ligase Grs1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543181, updated on 18-Sep-2024

    Summary

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    Official Symbol
    grs1
    Official Full Name
    glycine--tRNA (Gly) ligase Grs1
    Primary source
    PomBase:SPAC3F10.03
    Locus tag
    SPOM_SPAC3F10.03
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See grs1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (2821360..2823619)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene MCM complex subunit Mcm5 Neighboring gene plasma membrane potassium ion transmembrane transporter Trk1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene glutathione synthetase large and small subunit Gsa1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. One of two genes encoding glycyl-tRNA synthetase in Saccharomyces cerevisiae provides mitochondrial and cytoplasmic functions. Turner RJ, et al. J Biol Chem, 2000 Sep 8. PMID 10874035
    2. Dephosphorylation of F-BAR protein Cdc15 modulates its conformation and stimulates its scaffolding activity at the cell division site. Roberts-Galbraith RH, et al. Mol Cell, 2010 Jul 9. PMID 20603077, Free PMC Article
    3. Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase. Chen JS, et al. Mol Cell Proteomics, 2013 May. PMID 23297348, Free PMC Article
    4. A Two-step Protein Quality Control Pathway for a Misfolded DJ-1 Variant in Fission Yeast. Mathiassen SG, et al. J Biol Chem, 2015 Aug 21. PMID 26152728, Free PMC Article
    5. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables ATP:ATP adenylyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycine-tRNA ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables glycine-tRNA ligase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    		  
    involved_in diadenosine tetraphosphate biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in glycyl-tRNA aminoacylation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in mitochondrial glycyl-tRNA aminoacylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in mitochondrial matrix IC
    Inferred by Curator
    more info
    		  
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitochondrion IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glycine--tRNA (Gly) ligase Grs1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2821360..2823619
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019363.3 → NP_593935.1  glycine--tRNA (Gly) ligase Grs1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593935.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q10179
      Conserved Domains (1) summary
      PLN02734
      Location:3 → 644
      PLN02734; glycyl-tRNA synthetase
    Nucleotide Protein
    Heading Accession and Version

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