U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    swc4 Swr1 complex/NuA4 histone acetyltransferase complex subunit Swc4 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542412, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    swc4
    Official Full Name
    Swr1 complex/NuA4 histone acetyltransferase complex subunit Swc4
    Primary source
    PomBase:SPAC9G1.13c
    Locus tag
    SPOM_SPAC9G1.13C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See swc4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003424.3 (1995130..1996716, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene PAK-like GC kinase Sid1 Neighboring gene inositol polyphosphate phosphatase Neighboring gene ncRNA Neighboring gene mitotic septin Spn4 Neighboring gene tRNA (m1A) methyltransferase complex catalytic subunit Trm61 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene dynamin family protein Vps1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Activity of a C-terminal plant homeodomain (PHD) of Msc1 is essential for function. Qiu X, et al. J Biol Chem, 2010 Nov 19. PMID 20858896, Free PMC Article
    2. Histone variant H2A.Z regulates centromere silencing and chromosome segregation in fission yeast. Hou H, et al. J Biol Chem, 2010 Jan 15. PMID 19910462, Free PMC Article
    3. An acetylated form of histone H2A.Z regulates chromosome architecture in Schizosaccharomyces pombe. Kim HS, et al. Nat Struct Mol Biol, 2009 Dec. PMID 19915592, Free PMC Article
    4. Chaperone-mediated ordered assembly of the SAGA and NuA4 transcription co-activator complexes in yeast. Elías-Villalobos A, et al. Nat Commun, 2019 Nov 20. PMID 31748520, Free PMC Article
    5. Histone H2A.Z cooperates with RNAi and heterochromatin factors to suppress antisense RNAs. Zofall M, et al. Nature, 2009 Sep 17. PMID 19693008, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation-coupled chromatin remodeling IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of NuA4 histone acetyltransferase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of NuA4 histone acetyltransferase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of Swr1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of Swr1 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Swr1 complex/NuA4 histone acetyltransferase complex subunit Swc4

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1995130..1996716 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019001.4 → NP_593568.2  Swr1 complex/NuA4 histone acetyltransferase complex subunit Swc4 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593568.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14308
      Conserved Domains (1) summary
      pfam16282
      Location:101 → 179
      SANT_DAMP1_like; SANT/Myb-like domain of DAMP1
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials