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    UBX7 Ubx7p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852576, updated on 9-Dec-2024

    Summary

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    Official Symbol
    UBX7
    Official Full Name
    Ubx7p
    Primary source
    SGD:S000000477
    Locus tag
    YBR273C
    See related
    AllianceGenome:SGD:S000000477; FungiDB:YBR273C; VEuPathDB:YBR273C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    CUI3
    Summary
    Involved in sporulation resulting in formation of a cellular spore and ubiquitin-dependent protein catabolic process. Located in nuclear envelope. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See UBX7 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (748061..749371, complement)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene S-adenosylmethionine-dependent methyltransferase Neighboring gene Hsm3p Neighboring gene serine/threonine protein kinase CHK1 Neighboring gene DNA-binding protein RIF1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Binding of Cdc48p to a ubiquitin-related UBX domain from novel yeast proteins involved in intracellular proteolysis and sporulation. Decottignies A, et al. Yeast, 2004 Jan 30. PMID 14755638
    2. The UBX domain: a widespread ubiquitin-like module. Buchberger A, et al. J Mol Biol, 2001 Mar 16. PMID 11243799
    3. Diversification at transcription factor binding sites within a species and the implications for environmental adaptation. Ames RM, et al. Mol Biol Evol, 2011 Dec. PMID 21693437
    4. The F-box Protein Rcy1 Is Involved in the Degradation of Histone H3 Variant Cse4 and Genome Maintenance. Cheng H, et al. J Biol Chem, 2016 May 6. PMID 26975376, Free PMC Article
    5. Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation. Schuberth C, et al. EMBO Rep, 2004 Aug. PMID 15258615, Free PMC Article

    See all (41) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in ERAD pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sporulation resulting in formation of a cellular spore IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Ubx7p
    NP_009832.1
    • UBX (ubiquitin regulatory X) domain-containing protein; interacts with Cdc48p; UBX7 has a paralog, UBX6, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      748061..749371 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178621.1 → NP_009832.1  TPA: Ubx7p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009832.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQR9, P38349
      UniProtKB/TrEMBL
      B3LMN9, G2W9S7, N1P8M9
      Conserved Domains (1) summary
      pfam00789
      Location:213 → 292
      UBX; UBX domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38349.1

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