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    hbs1 translation release factor complex GTPase subunit [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540430, updated on 18-Sep-2024

    Summary

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    Official Symbol
    hbs1
    Official Full Name
    translation release factor complex GTPase subunit
    Primary source
    PomBase:SPBC25B2.01
    Locus tag
    SPOM_SPBC25B2.01
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPBC2G5.08
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    Genomic context

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    See hbs1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (2594345..2596452)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase III complex subunit Rpc25 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene M-factor transmembrane transporter Mam1 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structure of the Dom34-Hbs1 complex and implications for no-go decay. Chen L, et al. Nat Struct Mol Biol, 2010 Oct. PMID 20890290
    2. Regulated Ire1-dependent mRNA decay requires no-go mRNA degradation to maintain endoplasmic reticulum homeostasis in S. pombe. Guydosh NR, et al. Elife, 2017 Sep 25. PMID 28945192, Free PMC Article
    3. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
    4. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article
    5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables GTP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables translation release factor activity IC
    Inferred by Curator
    more info
    		  
    Process Evidence Code Pubs
    involved_in cytoplasmic translational termination IC
    Inferred by Curator
    more info
    		  
    involved_in endoplasmic reticulum unfolded protein response IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nuclear-transcribed mRNA catabolic process, no-go decay ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Dom34-Hbs1 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 

    General protein information

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    Preferred Names
    translation release factor complex GTPase subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2594345..2596452
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001355780.2 → NP_001342767.1  translation release factor complex GTPase subunit [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74774
      Conserved Domains (2) summary
      COG5256
      Location:171 → 592
      TEF1; Translation elongation factor EF-1alpha (GTPase) [Translation, ribosomal structure and biogenesis]
      pfam08938
      Location:34 → 80
      HBS1_N; HBS1 N-terminus
    Nucleotide Protein
    Heading Accession and Version

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