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    ura5 orotate phosphoribosyltransferase Ura5 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541166, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ura5
    Official Full Name
    orotate phosphoribosyltransferase Ura5
    Primary source
    PomBase:SPBC725.15
    Locus tag
    SPOM_SPBC725.15
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See ura5 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (1231043..1232358)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene borealin N terminal domain-containing protein Neighboring gene GINS complex subunit Psf2 Neighboring gene ncRNA Neighboring gene acetylglutamate synthase Arg6 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene MBF transcription factor complex subunit Res1 Neighboring gene ncRNA Neighboring gene RNA polymerase I transcription factor subunit Rrn11

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Use of a ura5+-lys7+ cassette to construct unmarked gene knock-ins in Schizosaccharomyces pombe. Mudge DK, et al. Curr Genet, 2012 Feb. PMID 22198627
    2. Polypeptone induces dramatic cell lysis in ura4 deletion mutants of fission yeast. Matsuo Y, et al. PLoS One, 2013. PMID 23555823, Free PMC Article
    3. Large scale screening of genetic interaction with sgf73(+) in fission yeast. Guo Y, et al. Yi Chuan, 2014 Jul. PMID 25076038
    4. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
    5. Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex. Stewart EV, et al. Mol Cell, 2011 Apr 22. PMID 21504829, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables orotate phosphoribosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in 'de novo' UMP biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in 'de novo' pyrimidine nucleobase biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in 'de novo' pyrimidine nucleobase biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in pyrimidine nucleotide biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in pyrimidine ribonucleoside biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    orotate phosphoribosyltransferase Ura5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1231043..1232358
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021406.3 → NP_595495.1  orotate phosphoribosyltransferase Ura5 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595495.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94331
      Conserved Domains (1) summary
      PRK00455
      Location:1 → 212
      pyrE; orotate phosphoribosyltransferase; Validated
    Nucleotide Protein
    Heading Accession and Version

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