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    ryh1 Rab family GTPase Ryh1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543529, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ryh1
    Official Full Name
    Rab family GTPase Ryh1
    Primary source
    PomBase:SPAC4C5.02c
    Locus tag
    SPOM_SPAC4C5.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    hos1; sat7
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    Genomic context

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    See ryh1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003424.3 (1192702..1195145, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene pseudouridine-5'-phosphatase Pud1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene multispanning membrane protein, CTNS/PQ domain protein Neighboring gene ncRNA Neighboring gene tRNA-Ala

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The ryh1 gene in the fission yeast Schizosaccharomyces pombe encoding a GTP-binding protein related to ras, rho and ypt: structure, expression and identification of its human homologue. Hengst L, et al. EMBO J, 1990 Jun. PMID 2112088, Free PMC Article
    2. Genetic and functional interaction between Ryh1 and Ypt3: two Rab GTPases that function in S. pombe secretory pathway. He Y, et al. Genes Cells, 2006 Mar. PMID 16483310
    3. Isolation of a fission yeast mutant that is sensitive to valproic acid and defective in the gene encoding Ric1, a putative component of Ypt/Rab-specific GEF for Ryh1 GTPase. Ma Y, et al. Mol Genet Genomics, 2010 Sep. PMID 20623139
    4. Functional link between Rab GTPase-mediated membrane trafficking and PI4,5P2 signaling. Li C, et al. Genes Cells, 2014 Mar. PMID 24350606
    5. Multiple crosstalk between TOR and the cell integrity MAPK signaling pathway in fission yeast. Madrid M, et al. Sci Rep, 2016 Nov 23. PMID 27876895, Free PMC Article

    See all (26) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables GTP binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein kinase regulator activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intra-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of TORC2 signaling EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in positive regulation of TORC2 signaling IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein localization to phagophore assembly site IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in retrograde transport, endosome to Golgi IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in endomembrane system IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    Rab family GTPase Ryh1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1192702..1195145 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001018646.3 → NP_593249.1  Rab family GTPase Ryh1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593249.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P17608
      Conserved Domains (2) summary
      smart00175
      Location:12 → 170
      RAB; Rab subfamily of small GTPases
      cd01861
      Location:12 → 172
      Rab6; Rab GTPase family 6 (Rab6)
    Nucleotide Protein
    Heading Accession and Version

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