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    ssr2 SWI/SNF and RSC complex subunit Ssr2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541851, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ssr2
    Official Full Name
    SWI/SNF and RSC complex subunit Ssr2
    Primary source
    PomBase:SPAC23H3.10
    Locus tag
    SPOM_SPAC23H3.10
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See ssr2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (2511081..2512846)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene threonine aldolase Gly1 Neighboring gene ncRNA Neighboring gene tRNA-Cys Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene glucosidase Neighboring gene ncRNA Neighboring gene hydrogen/potassium transport protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Fission yeast SWI/SNF and RSC complexes show compositional and functional differences from budding yeast. Monahan BJ, et al. Nat Struct Mol Biol, 2008 Aug. PMID 18622392, Free PMC Article
    2. Rbm10 facilitates heterochromatin assembly via the Clr6 HDAC complex. Weigt M, et al. Epigenetics Chromatin, 2021 Jan 19. PMID 33468217, Free PMC Article
    3. Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries. Wang J, et al. Genes Dev, 2013 Sep 1. PMID 24013502, Free PMC Article
    4. Systematic analysis reveals the prevalence and principles of bypassable gene essentiality. Li J, et al. Nat Commun, 2019 Mar 1. PMID 30824696, Free PMC Article
    5. Predicting the fission yeast protein interaction network. Pancaldi V, et al. G3 (Bethesda), 2012 Apr. PMID 22540037, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables DNA binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables histone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in transcription initiation-coupled chromatin remodeling IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of RSC-type complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of SWI/SNF complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of SWI/SNF complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm HDA PubMed 

    General protein information

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    Preferred Names
    SWI/SNF and RSC complex subunit Ssr2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2511081..2512846
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019229.3 → NP_593800.1  SWI/SNF and RSC complex subunit Ssr2 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593800.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14470, P78877
      Conserved Domains (5) summary
      COG5259
      Location:1 → 503
      RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
      cd00167
      Location:249 → 291
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      cd02336
      Location:192 → 224
      ZZ_RSC8; Zinc finger, ZZ type. Zinc finger present in RSC8 and related proteins. RSC8 is a component of the RSC complex, which is closely related to the SWI/SNF complex and is involved in remodeling chromatin structure. The ZZ motif coordinates a zinc ion and ...
      pfam04433
      Location:21 → 106
      SWIRM; SWIRM domain
      pfam16495
      Location:369 → 449
      SWIRM-assoc_1; SWIRM-associated region 1
    Nucleotide Protein
    Heading Accession and Version

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