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    hob3 BAR adaptor protein Hob3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541160, updated on 18-Sep-2024

    Summary

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    Official Symbol
    hob3
    Official Full Name
    BAR adaptor protein Hob3
    Primary source
    PomBase:SPBC725.09c
    Locus tag
    SPOM_SPBC725.09C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See hob3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (1221744..1223205, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene peroxisomal targeting signal receptor Pex5 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene C2H2-type zinc finger domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene tspO-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Hob3p, the fission yeast ortholog of human BIN3, localizes Cdc42p to the division site and regulates cytokinesis. Coll PM, et al. EMBO J, 2007 Apr 4. PMID 17363901, Free PMC Article
    2. hob1+, the fission yeast homolog of Bin1, is dispensable for endocytosis or actin organization, but required for the response to starvation or genotoxic stress. Routhier EL, et al. Oncogene, 2003 Feb 6. PMID 12569356
    3. Human BIN3 complements the F-actin localization defects caused by loss of Hob3p, the fission yeast homolog of Rvs161p. Routhier EL, et al. J Biol Chem, 2001 Jun 15. PMID 11274158
    4. Proximity-dependent biotinylation mediated by TurboID to identify protein-protein interaction networks in yeast. Larochelle M, et al. J Cell Sci, 2019 May 31. PMID 31064814
    5. Expanded Interactome of the Intrinsically Disordered Protein Dss1. Schenstrøm SM, et al. Cell Rep, 2018 Oct 23. PMID 30355493, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables cytoskeletal protein-membrane anchor activity ISM
    Inferred from Sequence Model
    more info
    		  
    contributes_to lipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cortical patch localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in actin cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic actomyosin contractile ring assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in plasma membrane tubulation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Rvs161p-Rvs167p complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in actin cortical patch IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cell cortex of cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mating projection tip IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in medial cortex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in medial cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    BAR adaptor protein Hob3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1221744..1223205 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021400.3 → NP_595489.1  BAR adaptor protein Hob3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595489.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P78850, Q9UUM7
      Conserved Domains (1) summary
      cd07591
      Location:20 → 241
      BAR_Rvs161p; The Bin/Amphiphysin/Rvs (BAR) domain of Saccharomyces cerevisiae Reduced viability upon starvation protein 161 and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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