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    apc15 anaphase-promoting complex platform subcomplex scaffold subunit Apc15 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540655, updated on 18-Sep-2024

    Summary

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    Official Symbol
    apc15
    Official Full Name
    anaphase-promoting complex platform subcomplex scaffold subunit Apc15
    Primary source
    PomBase:SPBC83.04
    Locus tag
    SPOM_SPBC83.04
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See apc15 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (1516696..1517574)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene RITS complex subunit 3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RNA-binding protein Yme2 Neighboring gene ncRNA Neighboring gene mitochondrial 54S ribosomal protein bL36m Neighboring gene Lid2 complex histone demethylase H3-K36 subunit Jmj3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determinants of robustness in spindle assembly checkpoint signalling. Heinrich S, et al. Nat Cell Biol, 2013 Nov. PMID 24161933
    2. Fission Yeast Apc15 Stabilizes MCC-Cdc20-APC/C Complexes, Ensuring Efficient Cdc20 Ubiquitination and Checkpoint Arrest. May KM, et al. Curr Biol, 2017 Apr 24. PMID 28366744, Free PMC Article
    3. Role of Hcn1 and its phosphorylation in fission yeast anaphase-promoting complex/cyclosome function. Yoon HJ, et al. J Biol Chem, 2006 Oct 27. PMID 16950791
    4. Structural organization of the anaphase-promoting complex bound to the mitotic activator Slp1. Ohi MD, et al. Mol Cell, 2007 Dec 14. PMID 18082611, Free PMC Article
    5. The spindle checkpoint functions of Mad3 and Mad2 depend on a Mad3 KEN box-mediated interaction with Cdc20-anaphase-promoting complex (APC/C). Sczaniecka M, et al. J Biol Chem, 2008 Aug 22. PMID 18556659, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in anaphase-promoting complex-dependent catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of anaphase-promoting complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    anaphase-promoting complex platform subcomplex scaffold subunit Apc15

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1516696..1517574
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021530.3 → NP_595636.1  anaphase-promoting complex platform subcomplex scaffold subunit Apc15 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595636.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94688
      Conserved Domains (1) summary
      pfam10446
      Location:64 → 134
      DUF2457; Protein of unknown function (DUF2457)
    Nucleotide Protein
    Heading Accession and Version

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