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    EDS1 Eds1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852321, updated on 9-Dec-2024

    Summary

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    Official Symbol
    EDS1
    Official Full Name
    Eds1p
    Primary source
    SGD:S000000237
    Locus tag
    YBR033W
    See related
    AllianceGenome:SGD:S000000237; FungiDB:YBR033W; VEuPathDB:YBR033W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables sequence-specific DNA binding activity. Predicted to be involved in nitrogen catabolite activation of transcription from RNA polymerase II promoter. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See EDS1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_001134.8 (301944..304703)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene ribosomal 60S subunit protein L4A Neighboring gene uncharacterized protein Neighboring gene protein-arginine omega-N methyltransferase HMT1 Neighboring gene pyridoxamine-phosphate oxidase PDX3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Rapid identification and differentiation of Saccharomyces cerevisiae, Saccharomyces bayanus and their hybrids by multiplex PCR. Torriani S, et al. Lett Appl Microbiol, 2004. PMID 14962047
    2. Identifying cooperative transcription factors by combining ChIP-chip data and knockout data. Yang Y, et al. Cell Res, 2010 Nov. PMID 20975739
    3. Phenotypic analysis of genes encoding yeast zinc cluster proteins. Akache B, et al. Nucleic Acids Res, 2001 May 15. PMID 11353088, Free PMC Article
    4. A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters. Badis G, et al. Mol Cell, 2008 Dec 26. PMID 19111667, Free PMC Article
    5. Recruitment of Rpd3 to the telomere depends on the protein arginine methyltransferase Hmt1. Milliman EJ, et al. PLoS One, 2012. PMID 22953000, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding HDA PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Eds1p
    NP_009589.1
    • Putative zinc cluster protein, predicted to be a transcription factor; not an essential gene; EDS1 has a paralog, RGT1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      301944..304703
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178381.1 → NP_009589.1  TPA: Eds1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009589.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A6ZKX7, B3LNB2, B5VDZ9, D6VQ33, P38073
      Conserved Domains (1) summary
      pfam00172
      Location:54 → 95
      Zn_clus; Fungal Zn(2)-Cys(6) binuclear cluster domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38073.1

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