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    PHM7 Phm7p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854070, updated on 9-Dec-2024

    Summary

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    Official Symbol
    PHM7
    Official Full Name
    Phm7p
    Primary source
    SGD:S000005444
    Locus tag
    YOL084W
    See related
    AllianceGenome:SGD:S000005444; FungiDB:YOL084W; VEuPathDB:YOL084W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable calcium-activated cation channel activity. Involved in phosphate ion transport. Located in endoplasmic reticulum and fungal-type vacuole. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See PHM7 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (162356..165331)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene alcohol dehydrogenase ADH1 Neighboring gene uncharacterized protein Neighboring gene Atg34p Neighboring gene Atg19p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PHM6 and PHM7 genes are essential for phosphate surplus in the cells of Saccharomyces cerevisiae. Kulakovskaya E, et al. Arch Microbiol, 2023 Jan 2. PMID 36592238
    2. The Reduced Level of Inorganic Polyphosphate Mobilizes Antioxidant and Manganese-Resistance Systems in Saccharomyces cerevisiae. Trilisenko L, et al. Cells, 2019 May 15. PMID 31096715, Free PMC Article
    3. New components of a system for phosphate accumulation and polyphosphate metabolism in Saccharomyces cerevisiae revealed by genomic expression analysis. Ogawa N, et al. Mol Biol Cell, 2000 Dec. PMID 11102525, Free PMC Article
    4. Yeast Ssd1 is a non-enzymatic member of the RNase II family with an alternative RNA recognition site. Bayne RA, et al. Nucleic Acids Res, 2022 Mar 21. PMID 34302485, Free PMC Article
    5. Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes. Dixon SJ, et al. Proc Natl Acad Sci U S A, 2008 Oct 28. PMID 18931302, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PHM6 and PHM7 genes are essential for phosphate surplus in the cells of Saccharomyces cerevisiae.
      Title: PHM6 and PHM7 genes are essential for phosphate surplus in the cells of Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables calcium-activated cation channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables calcium-activated cation channel activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in monoatomic cation transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phosphate ion transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    located_in fungal-type vacuole HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Phm7p
    NP_014557.1
    • hypothetical protein; expression is regulated by phosphate levels; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole; protein abundance increases in response to DNA replication stress

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      162356..165331
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183338.1 → NP_014557.1  TPA: Phm7p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014557.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1Y4, Q12252
      UniProtKB/TrEMBL
      G2WMF1, N1NXM8
      Conserved Domains (1) summary
      COG5594
      Location:4 → 985
      COG5594; Uncharacterized integral membrane protein [Function unknown]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12252.1

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