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    DIA3 putative acid phosphatase DIA3 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851537, updated on 9-Dec-2024

    Summary

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    Official Symbol
    DIA3
    Official Full Name
    putative acid phosphatase DIA3
    Primary source
    SGD:S000002182
    Locus tag
    YDL024C
    See related
    AllianceGenome:SGD:S000002182; FungiDB:YDL024C; VEuPathDB:YDL024C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable acid phosphatase activity. Involved in invasive growth in response to glucose limitation and pseudohyphal growth. Located in fungal-type cell wall. Human ortholog(s) of this gene implicated in papillary thyroid carcinoma and pontocerebellar hypoplasia type 16. Orthologous to human MINPP1 (multiple inositol-polyphosphate phosphatase 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See DIA3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (408451..409857, complement)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Mrx9p Neighboring gene putative serine/threonine protein kinase RTK1 Neighboring gene uncharacterized protein Neighboring gene tRNA-Ala Neighboring gene glycerol-3-phosphate dehydrogenase (NAD(+)) GPD1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence-based approach for identification of cell wall proteins in Saccharomyces cerevisiae. Terashima H, et al. Curr Genet, 2002 Feb. PMID 11935221
    2. Genetic analysis reveals that FLO11 upregulation and cell polarization independently regulate invasive growth in Saccharomyces cerevisiae. Palecek SP, et al. Genetics, 2000 Nov. PMID 11063681, Free PMC Article
    3. The yeast Ess1 prolyl isomerase controls Swi6 and Whi5 nuclear localization. Atencio D, et al. G3 (Bethesda), 2014 Mar 20. PMID 24470217, Free PMC Article
    4. Rewiring of genetic networks in response to DNA damage. Bandyopadhyay S, et al. Science, 2010 Dec 3. PMID 21127252, Free PMC Article
    5. The nucleotide sequence of Saccharomyces cerevisiae chromosome IV. Jacq C, et al. Nature, 1997 May 29. PMID 9169867

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables acid phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables acid phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acid phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in invasive growth in response to glucose limitation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in pseudohyphal growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    is_active_in fungal-type cell wall IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    putative acid phosphatase DIA3
    NP_010260.1
    • hypothetical protein; involved in invasive and pseudohyphal growth

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      408451..409857 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180083.1 → NP_010260.1  TPA: putative acid phosphatase DIA3 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010260.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRW7, P52290
      UniProtKB/TrEMBL
      B3LGS8, B5VFP1, C8Z4P5, N1PAA9
      Conserved Domains (1) summary
      pfam00328
      Location:66 → 400
      His_Phos_2; Histidine phosphatase superfamily (branch 2)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P52290.1

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