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    LSO1 Lso1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 1466469, updated on 9-Dec-2024

    Summary

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    Official Symbol
    LSO1
    Official Full Name
    Lso1p
    Primary source
    SGD:S000028523
    Locus tag
    YJR005C-A
    See related
    AllianceGenome:SGD:S000028523; FungiDB:YJR005C-A; VEuPathDB:YJR005C-A
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in intracellular iron ion homeostasis. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See LSO1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (448477..448758, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Sag1p Neighboring gene Apl1p Neighboring gene DNA-directed DNA polymerase delta subunit POL31 Neighboring gene translation initiation factor eIF2 subunit alpha

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001142.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The late-annotated small ORF LSO1 is a target gene of the iron regulon of Saccharomyces cerevisiae. An X, et al. Microbiologyopen, 2015 Dec. PMID 26450372, Free PMC Article
    2. A chemical potentiator of copper-accumulation used to investigate the iron-regulons of Saccharomyces cerevisiae. Foster AW, et al. Mol Microbiol, 2014 Jul. PMID 24895027, Free PMC Article
    3. Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii. Brachat S, et al. Genome Biol, 2003. PMID 12844361, Free PMC Article
    4. Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X. Galibert F, et al. EMBO J, 1996 May 1. PMID 8641269, Free PMC Article
    5. A global genetic interaction network maps a wiring diagram of cellular function. Costanzo M, et al. Science, 2016 Sep 23. PMID 27708008, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. LSO1 and LSO2 appear to play overlapping roles in the cellular response to iron starvation.
      Title: The late-annotated small ORF LSO1 is a target gene of the iron regulon of Saccharomyces cerevisiae.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular iron ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Lso1p
    NP_878106.1
    • Protein with a potential role in response to iron deprivation; transcription increases during iron deprivation and during treatment with 2-(6-benzyl-2-pyridyl)quinazoline (BPQ) and copper; regulated by Aft1p and, to a lesser extent, by Aft2p; originally identified as a syntenic homolog of an Ashbya gossypii gene; localizes to nucleus and cytoplasm, and nuclear localization is enhanced under iron-replete conditions

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      448477..448758 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184533.1 → NP_878106.1  TPA: Lso1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_878106.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWI0, Q3E827
      UniProtKB/TrEMBL
      A6ZPX2, B3LQA4, C7GUT6, D3UF72, G2WH15, N1P8L6
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3E827.1

    Gene LinkOut

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