IMP2 endopeptidase catalytic subunit [Saccharomyces cerevisiae S288C] - Gene

Summary

Official Symbol: IMP2
Official Full Name: endopeptidase catalytic subunit
Primary source: SGD:S000004638
Locus tag: YMR035W
See related: AllianceGenome:SGD:S000004638; FungiDB:YMR035W; VEuPathDB:YMR035W
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Saccharomyces cerevisiae S288C (strain: S288C)
Lineage: Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
Summary: Enables endopeptidase activity. Involved in protein processing involved in protein targeting to mitochondrion. Part of mitochondrial inner membrane peptidase complex. Orthologous to human IMMP2L (inner mitochondrial membrane peptidase subunit 2). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome XIII - NC_001145.3 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables endopeptidase activity	IBA Inferred from Biological aspect of Ancestor more info
enables endopeptidase activity	IDA Inferred from Direct Assay more info	PubMed
enables endopeptidase activity	IMP Inferred from Mutant Phenotype more info	PubMed
enables peptidase activity	IEA Inferred from Electronic Annotation more info
enables serine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein processing involved in protein targeting to mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein processing involved in protein targeting to mitochondrion	IEA Inferred from Electronic Annotation more info
involved_in protein processing involved in protein targeting to mitochondrion	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in proteolysis	IEA Inferred from Electronic Annotation more info
involved_in signal peptide processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
part_of mitochondrial inner membrane peptidase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of mitochondrial inner membrane peptidase complex	IEA Inferred from Electronic Annotation more info
part_of mitochondrial inner membrane peptidase complex	IPI Inferred from Physical Interaction more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

NP_013749.1

Catalytic subunit of mitochondrial inner membrane peptidase complex; required for maturation of mitochondrial proteins of the intermembrane space; complex contains two catalytic subunits (Imp1p and Imp2p that differ in substrate specificity), and Som1p

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The following sections contain reference sequences that belong to a specific genome build. Explain