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    hba1 Ran GTPase-binding protein Hba1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540948, updated on 14-Nov-2024

    Summary

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    Official Symbol
    hba1
    Official Full Name
    Ran GTPase-binding protein Hba1
    Primary source
    PomBase:SPBC365.13c
    Locus tag
    SPOM_SPBC365.13C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    caf1
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    Genomic context

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    See hba1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (2518726..2520843, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene Ino80 complex actin-like protein Arp5 Neighboring gene ncRNA Neighboring gene Golgi GRIP domain protein Grp2 Neighboring gene nuclear envelope Ish domain protein Ish1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene UDP-glucose 4-epimerase Uge1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of a nuclear protein conferring brefeldin A resistance in Schizosaccharomyces pombe. Turi TG, et al. J Biol Chem, 1996 Apr 12. PMID 8621569
    2. Cloning of caf1+, caf2+ and caf4+ from Schizosaccharomyces pombe: their involvement in multidrug resistance, UV and pH sensitivity. Benko Z, et al. Mol Gen Genet, 1998 Dec. PMID 9894913
    3. Fission yeast Ubr1 ubiquitin ligase influences the oxidative stress response via degradation of active Pap1 bZIP transcription factor in the nucleus. Kitamura K, et al. Mol Microbiol, 2011 May. PMID 21410566
    4. Schizosaccharomyces pombe cells lacking the Ran-binding protein Hba1 show a multidrug resistance phenotype due to constitutive nuclear accumulation of Pap1. Castillo EA, et al. J Biol Chem, 2003 Oct 17. PMID 12896976
    5. Caffeine-resistance in S. pombe: mutations in three novel caf genes increase caffeine tolerance and affect radiation sensitivity, fertility, and cell cycle. Benko Z, et al. Curr Genet, 1997 Jun. PMID 9211790

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables small GTPase binding ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein export from nucleus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Ran GTPase-binding protein Hba1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2518726..2520843 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001355776.2 → NP_001342890.1  Ran GTPase-binding protein Hba1 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q09146, Q9UU29
      Conserved Domains (2) summary
      cl17171
      Location:257 → 390
      PH-like; Pleckstrin homology-like domain
      cl26761
      Location:17 → 300
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version

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