U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    clr5 silencing factor Clr5 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542669, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    clr5
    Official Full Name
    silencing factor Clr5
    Primary source
    PomBase:SPAC29B12.08
    Locus tag
    SPOM_SPAC29B12.08
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See clr5 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (5428356..5431523)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene plasma membrane glutathione transmembrane transporter Pgt1 Neighboring gene WW domain-binding protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Epigenetic inheritance of transcriptional silencing and switching competence in fission yeast. Thon G, et al. Genetics, 1997 Mar. PMID 9055078, Free PMC Article
    2. H3K9me-independent gene silencing in fission yeast heterochromatin by Clr5 and histone deacetylases. Hansen KR, et al. PLoS Genet, 2011 Jan 6. PMID 21253571, Free PMC Article
    3. Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast. Nguyen TT, et al. Sci Rep, 2015 Feb 11. PMID 25669599, Free PMC Article
    4. Systematic analysis reveals the prevalence and principles of bypassable gene essentiality. Li J, et al. Nat Commun, 2019 Mar 1. PMID 30824696, Free PMC Article
    5. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. find that Clr5 controls gene expression at multiple chromosomal locations in addition to affecting the mating-type region
      Title: H3K9me-independent gene silencing in fission yeast heterochromatin by Clr5 and histone deacetylases.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in silent mating-type cassette heterochromatin formation EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in silent mating-type cassette heterochromatin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    silencing factor Clr5

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5428356..5431523
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020417.4 → NP_594986.3  silencing factor Clr5 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594986.3

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14030
      Conserved Domains (1) summary
      pfam14420
      Location:3 → 51
      Clr5; Clr5 domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials