U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    sep1 DNA-binding forkhead transcription factor Sep1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540866, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    sep1
    Official Full Name
    DNA-binding forkhead transcription factor Sep1
    Primary source
    PomBase:SPBC4C3.12
    Locus tag
    SPOM_SPBC4C3.12
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See sep1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3133220..3136104, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene DNA-directed RNA polymerase I complex large subunit Nuc1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene guanyl-nucleotide exchange factor

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The S. pombe sep1 gene encodes a nuclear protein that is required for periodic expression of the cdc15 gene. Zilahi E, et al. FEBS Lett, 2000 Sep 15. PMID 10996305
    2. Mycelial and syncytial growth in Schizosaccharomyces pombe induced by novel septation mutations. Sipiczki M, et al. J Cell Sci, 1993 Feb. PMID 8505375
    3. Periodic gene expression program of the fission yeast cell cycle. Rustici G, et al. Nat Genet, 2004 Aug. PMID 15195092
    4. Fkh2p and Sep1p regulate mitotic gene transcription in fission yeast. Buck V, et al. J Cell Sci, 2004 Nov 1. PMID 15509866
    5. A new transcription factor for mitosis: in Schizosaccharomyces pombe, the RFX transcription factor Sak1 works with forkhead factors to regulate mitotic expression. Garg A, et al. Nucleic Acids Res, 2015 Aug 18. PMID 25908789, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IC
    Inferred by Curator
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IC
    Inferred by Curator
    more info
    		  
    Component Evidence Code Pubs
    part_of M/G1 phase-specific MADS box-forkhead transcription factor complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    DNA-binding forkhead transcription factor Sep1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3133220..3136104 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022222.3 → NP_596301.1  DNA-binding forkhead transcription factor Sep1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596301.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O43058, P79006
      Conserved Domains (2) summary
      COG5025
      Location:20 → 663
      COG5025; Transcription factor of the Forkhead/HNF3 family [Transcription]
      pfam00250
      Location:128 → 214
      Forkhead; Forkhead domain
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.