U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    rpa43 DNA-directed RNA polymerase I complex subunit Rpa43 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540989, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    rpa43
    Official Full Name
    DNA-directed RNA polymerase I complex subunit Rpa43
    Primary source
    PomBase:SPBC3B9.07c
    Locus tag
    SPOM_SPBC3B9.07C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    rpa21
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See rpa43 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (4000467..4001243, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene protein TIM chaperone Neighboring gene ncRNA Neighboring gene autophagy-associated protein Atg3 Neighboring gene ncRNA Neighboring gene protein mago nashi Neighboring gene ncRNA Neighboring gene ESCRT II complex subunit Vps36

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. [Characteristics of the cDNA of the Schizosaccharomyces pombe rpa43+ gene: structural similarity of the Rpa43 subunit of RNA-polymerase I with the Rpc25 subunit of RNA-polymerase III]. Shpakovskiĭ GV, et al. Bioorg Khim, 1999 Oct. PMID 10645483
    2. The fission yeast RPA21 subunit of RNA polymerase I: an evolutionarily conserved subunit interacting with ribosomal DNA (rDNA) transcription factor Rrn3p for recruitment to rDNA promoter. Imazawa Y, et al. Genes Genet Syst, 2002 Jun. PMID 12207036
    3. The fission yeast protein Ker1p is an ortholog of RNA polymerase I subunit A14 in Saccharomyces cerevisiae and is required for stable association of Rrn3p and RPA21 in RNA polymerase I. Imazawa Y, et al. J Biol Chem, 2005 Mar 25. PMID 15647272
    4. Senataxin homologue Sen1 is required for efficient termination of RNA polymerase III transcription. Rivosecchi J, et al. EMBO J, 2019 Aug 15. PMID 31294478, Free PMC Article
    5. Conserved strategies of RNA polymerase I hibernation and activation. Heiss FB, et al. Nat Commun, 2021 Feb 3. PMID 33536435, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    contributes_to DNA-directed 5'-3' RNA polymerase activity ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in transcription elongation by RNA polymerase I EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in transcription elongation by RNA polymerase I IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in transcription initiation at RNA polymerase I promoter IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RNA polymerase I complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RNA polymerase I complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleolus HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    DNA-directed RNA polymerase I complex subunit Rpa43

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      4000467..4001243 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022587.3 → NP_596665.1  DNA-directed RNA polymerase I complex subunit Rpa43 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596665.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O43036
      Conserved Domains (2) summary
      pfam17875
      Location:83 → 170
      RPA43_OB; RPA43 OB domain in RNA Pol I
      cl04309
      Location:2 → 85
      RNAP_Rpb7_N_like; This conserved domain represents the N-terminal ribonucleoprotein (RNP) domain of the Rpb7 subunit of eukaryotic RNA polymerase (RNAP) II and its homologs, Rpa43 of eukaryotic RNAP I, Rpc25 of eukaryotic RNAP III, and RpoE (subunit E) of archaeal RNAP. ...
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.