U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    vps35 retromer complex subunit Vps35 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539462, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    vps35
    Official Full Name
    retromer complex subunit Vps35
    Primary source
    PomBase:SPCC777.13
    Locus tag
    SPOM_SPCC777.13
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See vps35 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003421.2 (1619366..1622409)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ER stress response thioredoxin family membrane disulfide oxidoreductase Neighboring gene mitochondrial ribosomal protein subunit L9 Neighboring gene ncRNA Neighboring gene protein Gta3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene serine/threonine protein kinase Prp4 Neighboring gene tRNA dihydrouridine synthase Dus4 Neighboring gene protein phosphatase regulatory subunit Ekc1

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Increased copper toxicity in Saccharomyces cerevisiae lacking VPS35, a component of the retromer and monogenic Parkinson disease gene in humans. Sowada N, et al. Biochem Biophys Res Commun, 2016 Aug 5. PMID 27262440
    2. Vacuolar protein sorting receptor in Schizosaccharomyces pombe. Iwaki T, et al. Microbiology (Reading), 2006 May. PMID 16622069
    3. Analysis of the SNARE Stx8 recycling reveals that the retromer-sorting motif has undergone evolutionary divergence. Yanguas F, et al. PLoS Genet, 2021 Mar. PMID 33788833, Free PMC Article
    4. Fitness profiling links topoisomerase II regulation of centromeric integrity to doxorubicin resistance in fission yeast. Nguyen TT, et al. Sci Rep, 2015 Feb 11. PMID 25669599, Free PMC Article
    5. Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth. Rallis C, et al. Biol Open, 2014 Feb 15. PMID 24463365, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular protein transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in retrograde transport, endosome to Golgi IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in retrograde transport, endosome to Golgi IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in endosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    is_active_in late endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of retromer complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of retromer complex IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    part_of retromer, cargo-selective complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    retromer complex subunit Vps35

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1619366..1622409
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023250.3 → NP_588260.2  retromer complex subunit Vps35 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588260.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74552, P78830
      Conserved Domains (1) summary
      pfam03635
      Location:14 → 775
      Vps35; Vacuolar protein sorting-associated protein 35
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.