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    hsp16 heat shock protein Hsp16 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540977, updated on 14-Nov-2024

    Summary

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    Official Symbol
    hsp16
    Official Full Name
    heat shock protein Hsp16
    Primary source
    PomBase:SPBC3E7.02c
    Locus tag
    SPOM_SPBC3E7.02C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See hsp16 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (2660139..2660992, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene Prp19 complex WD repeat protein Prp17 Neighboring gene 1-phosphatidylinositol-3-phosphate 5-kinase Fab1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene synembryn ric8-like protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Interaction of a small heat shock protein of the fission yeast, Schizosaccharomyces pombe, with a denatured protein at elevated temperature. Hirose M, et al. J Biol Chem, 2005 Sep 23. PMID 16055437
    2. Nonequivalence observed for the 16-meric structure of a small heat shock protein, SpHsp16.0, from Schizosaccharomyces pombe. Hanazono Y, et al. Structure, 2013 Feb 5. PMID 23273429
    3. Hsp16p is required for thermotolerance in nuclear mRNA export in fission yeast Schizosaccharomyces pombe. Yoshida J, et al. Cell Struct Funct, 2005 Feb. PMID 15840944
    4. Formation of non-toxic Aβ fibrils by small heat shock protein under heat-stress conditions. Sakono M, et al. Biochem Biophys Res Commun, 2013 Jan 25. PMID 23261462
    5. Characterization of a sHsp of Schizosaccharomyces pombe, SpHsp15.8, and the implication of its functional mechanism by comparison with another sHsp, SpHsp16.0. Sugino C, et al. Proteins, 2009 Jan. PMID 18543332

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The HSP16 monomers show nonequivalence in the interaction with neighboring monomers and conformations of the N- and C-terminal regions.
      Title: Nonequivalence observed for the 16-meric structure of a small heat shock protein, SpHsp16.0, from Schizosaccharomyces pombe.
    2. SpHsp16.0 is likely to interact with denatured CS in the dissociated state, while SpHsp15.8 is likely to interact with CS in a large complex.
      Title: Characterization of a sHsp of Schizosaccharomyces pombe, SpHsp15.8, and the implication of its functional mechanism by comparison with another sHsp, SpHsp16.0.
    3. SpHsp16.0 protects citrate synthase from thermal aggregation at 45 degrees C with high efficiency
      Title: Interaction of a small heat shock protein of the fission yeast, Schizosaccharomyces pombe, with a denatured protein at elevated temperature.
    4. Hsp16 is required for thermotolerance in nuclear mRNA export in Schizosaccharomyces.
      Title: Hsp16p is required for thermotolerance in nuclear mRNA export in fission yeast Schizosaccharomyces pombe.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein folding chaperone IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables unfolded protein binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cellular response to heat IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in cellular response to misfolded protein IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cellular response to unfolded protein IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein complex oligomerization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in response to heat IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in response to hydrogen peroxide IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in response to salt stress IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in protein aggregate center IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    heat shock protein Hsp16

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2660139..2660992 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022007.2 → NP_596091.1  heat shock protein Hsp16 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596091.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14368
      Conserved Domains (1) summary
      COG0071
      Location:1 → 143
      IbpA; Molecular chaperone IbpA, HSP20 family [Posttranslational modification, protein turnover, chaperones]
    Nucleotide Protein
    Heading Accession and Version

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