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    mis17 kinetochore protein Mis17 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 3361327, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mis17
    Official Full Name
    kinetochore protein Mis17
    Primary source
    PomBase:SPBC21.01
    Locus tag
    SPOM_SPBC21.01
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPBC776.19
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    Genomic context

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    See mis17 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (3214206..3215938)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene transcription factor TFIIK complex ubiquitin-protein ligase E3 subunit, Pmh1 Neighboring gene EVE domain (PUA-related) protein, implicated in tRNA metabolism (possible RNA binding domain associated with tRNA methyltransferases) Neighboring gene V-type ATPase inhibitor and disassembly protein linked to MTOR Neighboring gene mediator complex subunit Med8 Neighboring gene Ras1-Scd pathway protein Ral2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Kinetochore Components Required for Centromeric Chromatin Assembly Are Impacted by Msc1 in Schizosaccharomyces pombe. Gao C, et al. Genetics, 2017 Oct. PMID 28827290, Free PMC Article
    2. Negative Regulation of the Mis17-Mis6 Centromere Complex by mRNA Decay Pathway and EKC/KEOPS Complex in Schizosaccharomyces pombe. Xu X, et al. G3 (Bethesda), 2019 Jun 5. PMID 30967422, Free PMC Article
    3. Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres. Hayashi T, et al. Cell, 2004 Sep 17. PMID 15369671
    4. Fission yeast Scm3 mediates stable assembly of Cnp1/CENP-A into centromeric chromatin. Williams JS, et al. Mol Cell, 2009 Feb 13. PMID 19217403, Free PMC Article
    5. Fta2, an essential fission yeast kinetochore component, interacts closely with the conserved Mal2 protein. Kerres A, et al. Mol Biol Cell, 2006 Oct. PMID 16855021, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in CENP-A containing chromatin assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mitotic sister chromatid segregation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of Mis6-Sim4 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    kinetochore protein Mis17

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3214206..3215938
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022256.3 → NP_001018835.1  kinetochore protein Mis17 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_001018835.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94643
    Nucleotide Protein
    Heading Accession and Version

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