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    msh1 mismatch repair ATPase msh1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542833, updated on 18-Sep-2024

    Summary

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    Official Symbol
    msh1
    Official Full Name
    mismatch repair ATPase msh1
    Primary source
    PomBase:SPAC13F5.01c
    Locus tag
    SPOM_SPAC13F5.01C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPAC23C11.18c
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    Genomic context

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    See msh1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003424.3 (2169036..2172147, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Polo kinase Plo1 Neighboring gene ncRNA Neighboring gene putative potassium ion transporter Mdm28 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene transcription factor TFIID complex subunit Taf7 Neighboring gene ncRNA Neighboring gene glycerol dehydrogenase Gld1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity. McDonald KR, et al. PLoS Genet, 2016 Sep. PMID 27611590, Free PMC Article
    2. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article
    3. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article
    4. ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe. Matsuyama A, et al. Nat Biotechnol, 2006 Jul. PMID 16823372
    5. Transcription and RNA-processing in fission yeast mitochondria. Schäfer B, et al. RNA, 2005 May. PMID 15811919, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables ATP hydrolysis activity IC
    Inferred by Curator
    more info
    		  
    enables ATP-dependent DNA damage sensor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables double-stranded DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables mismatched DNA binding ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in mismatch repair ISM
    Inferred from Sequence Model
    more info
    		  
    involved_in mitochondrial DNA repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial chromosome IC
    Inferred by Curator
    more info
    		  
    is_active_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    mismatch repair ATPase msh1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2169036..2172147 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001019080.4 → NP_593649.2  mismatch repair ATPase msh1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_593649.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O13700, O13921, Q9USD9
      Conserved Domains (6) summary
      COG0249
      Location:55 → 941
      MutS; DNA mismatch repair ATPase MutS [Replication, recombination and repair]
      pfam00488
      Location:696 → 934
      MutS_V; MutS domain V
      pfam01624
      Location:72 → 176
      MutS_I; MutS domain I
      pfam05188
      Location:217 → 332
      MutS_II; MutS domain II
      pfam05192
      Location:348 → 459
      MutS_III; MutS domain III
      cl17822
      Location:552 → 648
      MutS_III; MutS domain III
    Nucleotide Protein
    Heading Accession and Version

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