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    fml2 ATP-dependent 3'-5'-directionality DNA helicase fml2 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542014, updated on 14-Nov-2024

    Summary

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    Official Symbol
    fml2
    Official Full Name
    ATP-dependent 3'-5'-directionality DNA helicase fml2
    Primary source
    PomBase:SPAC20H4.04
    Locus tag
    SPOM_SPAC20H4.04
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    mfh2
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    Genomic context

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    See fml2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (2116525..2120279)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene U3 snoRNP-associated protein Utp5 Neighboring gene protein dsc3 Neighboring gene general transcription elongation factor TFIIS Neighboring gene 5'-methylthioribulose-1-phosphate dehydratase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Gpl1-Gih35-Wdr83 complex RNA-binding subunit

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Essential domains of Schizosaccharomyces pombe Rad8 required for DNA damage response. Ding L, et al. G3 (Bethesda), 2014 May 28. PMID 24875629, Free PMC Article
    2. Large scale screening of genetic interaction with sgf73(+) in fission yeast. Guo Y, et al. Yi Chuan, 2014 Jul. PMID 25076038
    3. Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries. Wang J, et al. Genes Dev, 2013 Sep 1. PMID 24013502, Free PMC Article
    4. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article
    5. Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast. Roguev A, et al. Science, 2008 Oct 17. PMID 18818364, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables 3'-5' DNA helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables four-way junction DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables four-way junction helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in Okazaki fragment processing involved in mitotic DNA replication ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in double-strand break repair via synthesis-dependent strand annealing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in interstrand cross-link repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleolus HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    ATP-dependent 3'-5'-directionality DNA helicase fml2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      2116525..2120279
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001356051.2 → NP_001342977.1  ATP-dependent 3'-5'-directionality DNA helicase fml2 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9HE09
      Conserved Domains (1) summary
      COG1111
      Location:96 → 646
      MPH1; ERCC4-related helicase [Replication, recombination and repair]
    Nucleotide Protein
    Heading Accession and Version

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