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    rav1 RAVE complex subunit Rav1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539705, updated on 18-Sep-2024

    Summary

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    Official Symbol
    rav1
    Official Full Name
    RAVE complex subunit Rav1
    Primary source
    PomBase:SPBC1105.10
    Locus tag
    SPOM_SPBC1105.10
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See rav1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003423.3 (3524536..3528845)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ubiquitin-conjugating enzyme Ubc15 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene histone H3 h3.3 Neighboring gene uncharacterized protein Neighboring gene histone H4 h4.3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Calcium modulation of doxorubicin cytotoxicity in yeast and human cells. Nguyen TT, et al. Genes Cells, 2016 Mar. PMID 26891792
    2. P-glycoprotein and vacuolar ATPase synergistically confer anthracycline resistance to fission yeast and human cells. Tay Z, et al. Curr Med Chem, 2014. PMID 24059229
    3. Loss of regulators of vacuolar ATPase function and ceramide synthesis results in multidrug sensitivity in Schizosaccharomyces pombe. Dawson K, et al. Eukaryot Cell, 2008 Jun. PMID 18441123, Free PMC Article
    4. Cellular robustness conferred by genetic crosstalk underlies resistance against chemotherapeutic drug doxorubicin in fission yeast. Tay Z, et al. PLoS One, 2013. PMID 23365689, Free PMC Article
    5. Hierarchical modularity and the evolution of genetic interactomes across species. Ryan CJ, et al. Mol Cell, 2012 Jun 8. PMID 22681890, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein-containing complex binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in late endosome to vacuole transport TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in vacuolar acidification IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in vacuolar proton-transporting V-type ATPase complex assembly TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of RAVE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of RAVE complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in endosome membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    RAVE complex subunit Rav1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3524536..3528845
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022385.3 → NP_596466.1  RAVE complex subunit Rav1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596466.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9Y817
      Conserved Domains (1) summary
      pfam12234
      Location:576 → 1230
      Rav1p_C; RAVE protein 1 C terminal
    Nucleotide Protein
    Heading Accession and Version

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