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    NFG1 Nfg1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850731, updated on 9-Dec-2024

    Summary

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    Official Symbol
    NFG1
    Official Full Name
    Nfg1p
    Primary source
    SGD:S000004032
    Locus tag
    YLR042C
    See related
    AllianceGenome:SGD:S000004032; FungiDB:YLR042C; VEuPathDB:YLR042C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Acts upstream of or within negative regulation of filamentous growth. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See NFG1 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (229966..230451, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Ric1p Neighboring gene Afb1p Neighboring gene thioredoxin TRX1 Neighboring gene indolepyruvate decarboxylase 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The deletion of YLR042c improves ethanolic xylose fermentation by recombinant Saccharomyces cerevisiae. Parachin NS, et al. Yeast, 2010 Sep. PMID 20641017
    2. Identification of common traits in improved xylose-growing Saccharomyces cerevisiae for inverse metabolic engineering. Bengtsson O, et al. Yeast, 2008 Nov. PMID 19061191
    3. Transcriptional reporters for genes activated by cell wall stress through a non-catalytic mechanism involving Mpk1 and SBF. Kim KY, et al. Yeast, 2010 Aug. PMID 20641022, Free PMC Article
    4. New Aspects of Invasive Growth Regulation Identified by Functional Profiling of MAPK Pathway Targets in Saccharomyces cerevisiae. Vandermeulen MD, et al. Genetics, 2020 Sep. PMID 32665277, Free PMC Article
    5. Amino acid residues in the omega-minus region participate in cellular localization of yeast glycosylphosphatidylinositol-attached proteins. Hamada K, et al. J Bacteriol, 1999 Jul. PMID 10383953, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of filamentous growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in fungal-type vacuole HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Nfg1p
    NP_013143.1
    • Negative regulator of the filamentous growth pathway; inhibits invasive growth by dampening the activity of the filamentous MAPK pathway; localizes to the cell wall and to the vacuole and cell periphery in HTP studies; deletion improves xylose fermentation in industrially engineered strains; nonessential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      229966..230451 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181929.1 → NP_013143.1  TPA: Nfg1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013143.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VY44, Q07990
      UniProtKB/TrEMBL
      A7A0U7, B3LT13, B5VMX5, C7GU48, C8ZD14, N1NZ27
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q07990.1

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