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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850735, updated on 9-Dec-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000004036
    Locus tag
    YLR046C
    See related
    AllianceGenome:SGD:S000004036; FungiDB:YLR046C; VEuPathDB:YLR046C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Located in fungal-type vacuole. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (238001..238813, complement)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene indolepyruvate decarboxylase 1 Neighboring gene Stu2p Neighboring gene putative ferric-chelate reductase Neighboring gene ribosomal 40S subunit protein S0B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001144.5

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Loop 5 region is important for the activity of the long-chain base transporter Rsb1. Makuta H, et al. J Biochem, 2017 Feb 1. PMID 28175317
    2. Topology models for 37 Saccharomyces cerevisiae membrane proteins based on C-terminal reporter fusions and predictions. Kim H, et al. J Biol Chem, 2003 Mar 21. PMID 12524434
    3. Competitive promoter occupancy by two yeast paralogous transcription factors controlling the multidrug resistance phenomenon. Lucau-Danila A, et al. J Biol Chem, 2003 Dec 26. PMID 14512416
    4. Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone. Zhao R, et al. Cell, 2005 Mar 11. PMID 15766533
    5. Association of yeast Upf1p with direct substrates of the NMD pathway. Johansson MJ, et al. Proc Natl Acad Sci U S A, 2007 Dec 26. PMID 18087042, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in fungal-type vacuole HDA PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_013147.1
    • Putative membrane protein; member of the fungal lipid-translocating exporter (LTE) family of proteins; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; YLR046C has a paralog, RTA1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      238001..238813 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181933.1 → NP_013147.1  TPA: uncharacterized protein YLR046C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013147.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VY48, Q12253
      UniProtKB/TrEMBL
      A7A0V1, B3LT17, C7GT72
      Conserved Domains (1) summary
      pfam04479
      Location:40 → 250
      RTA1; RTA1 like protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q12253.1

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