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    PAM1 Pam1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851838, updated on 9-Dec-2024

    Summary

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    Official Symbol
    PAM1
    Official Full Name
    Pam1p
    Primary source
    SGD:S000002659
    Locus tag
    YDR251W
    See related
    AllianceGenome:SGD:S000002659; FungiDB:YDR251W; VEuPathDB:YDR251W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in pseudohyphal growth. Located in cellular bud neck and cellular bud tip. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See PAM1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (960614..963106)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene gluconokinase Neighboring gene uncharacterized protein Neighboring gene CCR4-NOT core subunit BTT1 Neighboring gene Met32p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional characteristics of Svl3 and Pam1 that are required for proper cell wall formation in yeast cells. Jin Y, et al. Yeast, 2020 Jul. PMID 32491201
    2. Overexpression of yeast PAM1 gene permits survival without protein phosphatase 2A and induces a filamentous phenotype. Hu GZ, et al. J Biol Chem, 1994 Feb 4. PMID 8106383
    3. Differentiated gene expression in cells within yeast colonies. Mináriková L, et al. Exp Cell Res, 2001 Dec 10. PMID 11716542
    4. Osw2 is required for proper assembly of glucan and/or mannan layers of the yeast spore wall. Pan HP, et al. J Biochem, 2018 Apr 1. PMID 29211891
    5. Identification of novel genes responsible for ethanol and/or thermotolerance by transposon mutagenesis in Saccharomyces cerevisiae. Kim HS, et al. Appl Microbiol Biotechnol, 2011 Aug. PMID 21556919

    See all (44) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Functional characteristics of Svl3 and Pam1 that are required for proper cell wall formation in yeast cells.
      Title: Functional characteristics of Svl3 and Pam1 that are required for proper cell wall formation in yeast cells.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in pseudohyphal growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cellular bud HDA PubMed 
    located_in cellular bud neck HDA PubMed 
    located_in cellular bud neck IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cellular bud tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Pam1p
    NP_010537.3
    • Essential hypothetical protein; exhibits variable expression during colony morphogenesis; overexpression permits survival without protein phosphatase 2A, inhibits growth, and induces a filamentous phenotype; PAM1 has a paralog, SVL3, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      960614..963106
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180559.3 → NP_010537.3  TPA: Pam1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010537.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VSN1, P37304, Q03789
      UniProtKB/TrEMBL
      A6ZYK3, N1P6Y6
      Conserved Domains (1) summary
      COG3883
      Location:363 → 435
      CwlO1; Uncharacterized N-terminal domain of peptidoglycan hydrolase CwlO [Function unknown]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P37304.2

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