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    prp1 U4/U6 x U5 tri-snRNP complex subunit Prp1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541185, updated on 18-Sep-2024

    Summary

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    Official Symbol
    prp1
    Official Full Name
    U4/U6 x U5 tri-snRNP complex subunit Prp1
    Primary source
    PomBase:SPBC6B1.07
    Locus tag
    SPOM_SPBC6B1.07
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    zer1
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    Genomic context

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    See prp1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (2641921..2644897)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene 2-oxoglutarate and Fe(2+) dioxygenase domain-containing protein 1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The prp1+ gene required for pre-mRNA splicing in Schizosaccharomyces pombe encodes a protein that contains TPR motifs and is similar to Prp6p of budding yeast. Urushiyama S, et al. Genetics, 1997 Sep. PMID 9286671, Free PMC Article
    2. Pre-mRNA splicing mutants of Schizosaccharomyces pombe. Potashkin J, et al. EMBO J, 1989 Feb. PMID 2721492, Free PMC Article
    3. Splicing functions and global dependency on fission yeast slu7 reveal diversity in spliceosome assembly. Banerjee S, et al. Mol Cell Biol, 2013 Aug. PMID 23754748, Free PMC Article
    4. Fission yeast Prp4p kinase regulates pre-mRNA splicing by phosphorylating a non-SR-splicing factor. Schwelnus W, et al. EMBO Rep, 2001 Jan. PMID 11252721, Free PMC Article
    5. Mutant allele of rna14 in fission yeast affects pre-mRNA splicing. Yadav S, et al. J Genet, 2016 Jun. PMID 27350684

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA cis splicing, via spliceosome EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in mRNA cis splicing, via spliceosome IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in mRNA splicing, via spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in spliceosomal tri-snRNP complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of U4/U6 x U5 tri-snRNP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of U4/U6 x U5 tri-snRNP complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of catalytic step 2 spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    U4/U6 x U5 tri-snRNP complex subunit Prp1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2641921..2644897
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022000.3 → NP_596086.1  U4/U6 x U5 tri-snRNP complex subunit Prp1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596086.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q12381
      Conserved Domains (3) summary
      smart00386
      Location:384 → 414
      HAT; HAT (Half-A-TPR) repeats
      sd00006
      Location:678 → 708
      TPR; TPR repeat [structural motif]
      pfam06424
      Location:13 → 157
      PRP1_N; PRP1 splicing factor, N-terminal
    Nucleotide Protein
    Heading Accession and Version

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