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    wss2 ubiquitin/metalloprotease fusion protein [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2538751, updated on 18-Sep-2024

    Summary

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    Official Symbol
    wss2
    Official Full Name
    ubiquitin/metalloprotease fusion protein
    Primary source
    PomBase:SPCC1442.07c
    Locus tag
    SPOM_SPCC1442.07C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    udp7
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    Genomic context

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    See wss2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    1
    Sequence:
    Chromosome: III; NC_003421.2 (1779522..1780601, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene protein Mic26 Neighboring gene ncRNA Neighboring gene proteasome core particle subunit alpha 2 Pre8 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene cytochrome c oxidase subunit VIb

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN. Stingele J, et al. Mol Cell, 2016 Nov 17. PMID 27871365, Free PMC Article
    2. Interaction of the anaphase-promoting complex/cyclosome and proteasome protein complexes with multiubiquitin chain-binding proteins. Seeger M, et al. J Biol Chem, 2003 May 9. PMID 12615927
    3. Genetic controls of DNA damage avoidance in response to acetaldehyde in fission yeast. Noguchi C, et al. Cell Cycle, 2017 Jan 2. PMID 27687866, Free PMC Article
    4. Dsc E3 ligase localization to the Golgi requires the ATPase Cdc48 and cofactor Ufd1 for activation of sterol regulatory element-binding protein in fission yeast. Burr R, et al. J Biol Chem, 2017 Sep 29. PMID 28821619, Free PMC Article
    5. Phosphorylation of the RNA-binding protein Zfs1 modulates sexual differentiation in fission yeast. Navarro FJ, et al. J Cell Sci, 2017 Dec 15. PMID 29084823, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metallopeptidase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables proteasome binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables proteasome binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables single-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transition metal ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables zinc ion binding ISM
    Inferred from Sequence Model
    more info
    		  
    Process Evidence Code Pubs
    involved_in DNA repair IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein sumoylation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    ubiquitin/metalloprotease fusion protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1779522..1780601 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023312.3 → NP_588321.1  ubiquitin/metalloprotease fusion protein [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588321.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94580
      Conserved Domains (2) summary
      pfam00240
      Location:9 → 71
      ubiquitin; Ubiquitin family
      cl19237
      Location:120 → 274
      DUF45; Protein of unknown function DUF45
    Nucleotide Protein
    Heading Accession and Version

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