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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 852520, updated on 9-Dec-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000000423
    Locus tag
    YBR219C
    See related
    AllianceGenome:SGD:S000000423; FungiDB:YBR219C; VEuPathDB:YBR219C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable acetyl-CoA transmembrane transporter activity. Predicted to be involved in acetyl-CoA transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 42. Orthologous to human SLC33A1 (solute carrier family 33 member 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_001134.8 (662499..663303, complement)

    Chromosome II - NC_001134.8Genomic Context describing neighboring genes Neighboring gene Atg12p Neighboring gene pyruvate carboxylase 2 Neighboring gene uncharacterized protein Neighboring gene pyruvate dehydrogenase (acetyl-transferring) subunit E1 beta Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001134.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SCRaMbLE: A Study of Its Robustness and Challenges through Enhancement of Hygromycin B Resistance in a Semi-Synthetic Yeast. Ong JY, et al. Bioengineering (Basel), 2021 Mar 23. PMID 33806931, Free PMC Article
    2. Functional dissection of the NuA4 histone acetyltransferase reveals its role as a genetic hub and that Eaf1 is essential for complex integrity. Mitchell L, et al. Mol Cell Biol, 2008 Apr. PMID 18212056, Free PMC Article
    3. Annotating novel genes by integrating synthetic lethals and genomic information. Schöner D, et al. BMC Syst Biol, 2008 Jan 14. PMID 18194531, Free PMC Article
    4. Heterozygous yeast deletion collection screens reveal essential targets of Hsp90. Franzosa EA, et al. PLoS One, 2011. PMID 22140548, Free PMC Article
    5. Functional profiling of the Saccharomyces cerevisiae genome. Giaever G, et al. Nature, 2002 Jul 25. PMID 12140549

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables acetyl-CoA transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in acetyl-CoA transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_009778.3
    • hypothetical protein; YBR219C is not an essential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001134.8 Reference assembly

      Range
      662499..663303 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001178567.3 → NP_009778.3  TPA: uncharacterized protein YBR219C [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009778.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VQL5, P38317
      UniProtKB/TrEMBL
      G2W9M2
      Conserved Domains (1) summary
      cl28910
      Location:1 → 100
      MFS; Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38317.1

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