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    ekc1 protein phosphatase regulatory subunit Ekc1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539511, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ekc1
    Official Full Name
    protein phosphatase regulatory subunit Ekc1
    Primary source
    PomBase:SPCC663.01c
    Locus tag
    SPOM_SPCC663.01C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPCC777.16c
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    Genomic context

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    See ekc1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    2
    Sequence:
    Chromosome: III; NC_003421.2 (1625987..1629374, complement)

    Chromosome III - NC_003421.2Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene retromer complex subunit Vps35 Neighboring gene ncRNA Neighboring gene serine/threonine protein kinase Prp4 Neighboring gene tRNA dihydrouridine synthase Dus4 Neighboring gene ncRNA Neighboring gene wtf element Wtf14 Neighboring gene wtf element Wtf15

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003421.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The role of Ppe1/PP6 phosphatase for equal chromosome segregation in fission yeast kinetochore. Goshima G, et al. EMBO J, 2003 Jun 2. PMID 12773390, Free PMC Article
    2. Phosphatases Generate Signal Specificity Downstream of Ssp1 Kinase in Fission Yeast. Deng L, et al. Mol Cell Biol, 2017 May 15. PMID 28223368, Free PMC Article
    3. Schizosaccharomyces pombe cell division cycle under limited glucose requires Ssp1 kinase, the putative CaMKK, and Sds23, a PP2A-related phosphatase inhibitor. Hanyu Y, et al. Genes Cells, 2009 May. PMID 19371376
    4. Suppressor screening reveals common kleisin-hinge interaction in condensin and cohesin, but different modes of regulation. Xu X, et al. Proc Natl Acad Sci U S A, 2019 May 28. PMID 31072933, Free PMC Article
    5. The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability. Calvo IA, et al. iScience, 2021 Nov 19. PMID 34805795, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein phosphatase activator activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein phosphatase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein phosphatase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of kinetochore assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulation of signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in signaling NAS
    Non-traceable Author Statement
    more info
    		  
    Component Evidence Code Pubs
    is_active_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of protein serine/threonine phosphatase complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein phosphatase regulatory subunit Ekc1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003421.2 Reference assembly

      Range
      1625987..1629374 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001023253.3 → NP_588263.2  protein phosphatase regulatory subunit Ekc1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_588263.2

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74511, O74554
      Conserved Domains (1) summary
      pfam04499
      Location:141 → 653
      SAPS; SIT4 phosphatase-associated protein
    Nucleotide Protein
    Heading Accession and Version

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