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    Acbp2 Acyl-CoA binding protein 2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38784, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Acbp2provided by FlyBase
    Official Full Name
    Acyl-CoA binding protein 2provided by FlyBase
    Primary source
    FLYBASE:FBgn0010387
    Locus tag
    Dmel_CG8627
    See related
    AllianceGenome:FB:FBgn0010387
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    ACBP; anon-WO0172774.131; BcDNA:RH39533; CG8627; dbi; Dbi; DBI; DmDBI; Dmel\CG8627
    Summary
    Predicted to enable long-chain fatty acyl-CoA binding activity. Predicted to be involved in fatty acid metabolic process and intracellular acyl-CoA homeostasis. Is expressed in several structures, including adult head; adult heart; amnioserosa; embryonic/larval fat body; and gut section. Orthologous to human DBI (diazepam binding inhibitor, acyl-CoA binding protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Acbp2 in Genome Data Viewer
    Location:
    65E4-65E4; 3-19 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7131863..7133463)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7124963..7126563)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Acyl-CoA binding protein 6 Neighboring gene Acyl-CoA binding protein 3 Neighboring gene melted Neighboring gene cornetto Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables fatty-acyl-CoA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables fatty-acyl-CoA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables fatty-acyl-CoA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in fatty acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intracellular acyl-CoA homeostasis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Acyl-CoA binding protein 2
    Names
    Acbp2-PA
    Acbp2-PB
    CG8627-PA
    CG8627-PB
    Diazepam-binding inhibitor
    acyl-CoA binding protein
    acyl-CoA-binding protein
    diazepam binding inhibitor
    diazepam-binding protein
    endozepine

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      7131863..7133463
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168192.3 → NP_729218.1  Acyl-CoA binding protein 2, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729218.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V1K8, P42281, Q9VS23
      UniProtKB/TrEMBL
      A0A1B2AIW6
      Related
      FBpp0076624
      Conserved Domains (1) summary
      cd00435
      Location:2 → 86
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...

    2. NM_079228.3 → NP_523952.2  Acyl-CoA binding protein 2, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523952.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A4V1K8, P42281, Q9VS23
      UniProtKB/TrEMBL
      A0A1B2AIW6
      Related
      FBpp0076625
      Conserved Domains (1) summary
      cd00435
      Location:2 → 86
      ACBP; Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P42281.1 P42281

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