Oatp74D Organic anion transporting polypeptide 74D [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: Oatp74Dprovided by FlyBase
Official Full Name: Organic anion transporting polypeptide 74Dprovided by FlyBase
Primary source: FLYBASE:FBgn0036732
Locus tag: Dmel_CG7571
See related: AllianceGenome:FB:FBgn0036732
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: CG7571; Dmel\CG7571; EcI; oatp 74D
Summary: Predicted to enable sodium-independent organic anion transmembrane transporter activity. Involved in ecdysone receptor signaling pathway and larval development. Located in intracellular membrane-bounded organelle and plasma membrane. Is expressed in several structures, including adult head; anterior endoderm anlage; foregut anlage in statu nascendi; mesectoderm; and midline primordium. Orthologous to human SLCO2B1 (solute carrier organic anion transporter family member 2B1) and SLCO3A1 (solute carrier organic anion transporter family member 3A1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3L	NT_037436.4 (17487118..17511693)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3L	NT_037436.3 (17480218..17504793)

Chromosome 3L - NT_037436.4 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Steroid Hormone Entry into the Brain Requires a Membrane Transporter in Drosophila.
Title: Steroid Hormone Entry into the Brain Requires a Membrane Transporter in Drosophila.

Submit: New GeneRIF Correction

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables organic anion transmembrane transporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables sodium-independent organic anion transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in ecdysone receptor signaling pathway	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in larval development	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in organic anion transport	ISS Inferred from Sequence or Structural Similarity more info
involved_in sodium-independent organic anion transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
is_active_in basolateral plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in intracellular membrane-bounded organelle	IDA Inferred from Direct Assay more info	PubMed
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed
located_in plasma membrane	ISS Inferred from Sequence or Structural Similarity more info

Names: CG7571-PA; CG7571-PC; CG7571-PD; CG7571-PE; Oatp74D-PA; Oatp74D-PC; Oatp74D-PD; Oatp74D-PE; ecdysone importer

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