U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    FLO5 flocculin FLO5 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856618, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    FLO5
    Official Full Name
    flocculin FLO5
    Primary source
    SGD:S000001254
    Locus tag
    YHR211W
    See related
    AllianceGenome:SGD:S000001254; FungiDB:YHR211W; VEuPathDB:YHR211W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables D-mannose binding activity. Involved in cell-substrate adhesion and flocculation. Located in fungal-type cell wall. [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See FLO5 in Genome Data Viewer
    Location:
    chromosome: VIII
    Exon count:
    1
    Sequence:
    Chromosome: VIII; NC_001140.6 (525392..528619)

    Chromosome VIII - NC_001140.6Genomic Context describing neighboring genes Neighboring gene S-adenosylmethionine-dependent methyltransferase Neighboring gene aldose 1-epimerase superfamily protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001140.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Studied transcriptome of a flocculent Saccharomyces cerevisiae strain with regards to the role of FLO5 during wine fermentation.
      Title: Different genetic responses to oenological conditions between a flocculent wine yeast and its FLO5 deleted strain: Insights from the transcriptome.
    2. importance of FLO5 gene in development of high flocculent characteristic of wine yeasts
      Title: Genetic diversity of FLO1 and FLO5 genes in wine flocculent Saccharomyces cerevisiae strains.
    3. Data show that the Flo5A structure suggests a model for recognition, where social non-self- instead of unsocial self-interactions are favored.
      Title: Structural basis of flocculin-mediated social behavior in yeast.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables D-mannose binding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell-substrate adhesion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in flocculation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in flocculation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in fungal-type cell wall IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in side of membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    flocculin FLO5
    NP_012081.1
    • Lectin-like cell wall protein (flocculin) involved in flocculation; binds mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile; important for co-flocculation with other yeasts, mediating interaction with specific species; FLO5 has a paralog, FLO1, that arose from a segmental duplication

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001140.6 Reference assembly

      Range
      525392..528619
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179342.1 → NP_012081.1  TPA: flocculin FLO5 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012081.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D3DLG0, P38894
      UniProtKB/TrEMBL
      K9LCY6
      Conserved Domains (3) summary
      pfam00624
      Location:503 → 540
      Flocculin; Flocculin repeat
      pfam07691
      Location:100 → 249
      PA14; PA14 domain
      pfam13928
      Location:784 → 825
      Flocculin_t3; Flocculin type 3 repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P38894.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools