U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    BI4 intron-encoded RNA maturase bI4 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854582, updated on 9-Dec-2024

    Summary

    Official Symbol
    BI4
    Official Full Name
    intron-encoded RNA maturase bI4
    Primary source
    SGD:S000007273
    Locus tag
    Q0120
    See related
    AllianceGenome:SGD:S000007273; FungiDB:Q0120; VEuPathDB:Q0120
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C, substrain: FY1679)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables RNA binding activity. Involved in Group I intron splicing and mitochondrial mRNA processing. Located in mitochondrion. Human ortholog(s) of this gene implicated in ovarian carcinoma and urinary bladder cancer. Orthologous to human MT-CYB (mitochondrially encoded cytochrome b). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See BI4 in Genome Data Viewer
    Sequence:
    Chromosome: MT; NC_001224.1 (36540..42251)

    Chromosome MT - NC_001224.1Genomic Context describing neighboring genes Neighboring gene F1F0 ATP synthase subunit a Neighboring gene tRNA-Glu Neighboring gene cytochrome b mRNA maturase bI2 Neighboring gene cytochrome b mRNA maturase bI3 Neighboring gene cytochrome b Neighboring gene tRNA-Ser Neighboring gene F0 ATP synthase subunit c

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables RNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in Group I intron splicing IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in Group I intron splicing IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitochondrial mRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    intron-encoded RNA maturase bI4
    NP_009316.1
    • Mitochondrial mRNA maturase; forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001224.1 Reference assembly

      Range
      36540..42251
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_009316.1 intron-encoded RNA maturase bI4 (mitochondrion) [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_009316.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      A0A0A7NYH9, P03879, Q02324, Q9ZZW6
      UniProtKB/TrEMBL
      G2HKE5
      Conserved Domains (4) summary
      COG1372
      Location:363592
      Hop; Intein/homing endonuclease [Replication, recombination and repair, Mobilome: prophages, transposons]
      cd00284
      Location:8207
      Cytochrome_b_N; Cytochrome b (N-terminus)/b6/petB: Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria, ...
      pfam00961
      Location:408495
      LAGLIDADG_1; LAGLIDADG endonuclease
      cl00193
      Location:208255
      cytochrome_b_C; Cytochrome b(C-terminus)/b6/petD: Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria, ...