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    MRP2 mitochondrial 37S ribosomal protein MRP2 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856295, updated on 4-Jan-2025

    Summary

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    Official Symbol
    MRP2
    Official Full Name
    mitochondrial 37S ribosomal protein MRP2
    Primary source
    SGD:S000006370
    Locus tag
    YPR166C
    See related
    AllianceGenome:SGD:S000006370; FungiDB:YPR166C; VEuPathDB:YPR166C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    uS14m
    Summary
    A structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Part of mitochondrial small ribosomal subunit. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 38. Orthologous to human MRPS14 (mitochondrial ribosomal protein S14). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See MRP2 in Genome Data Viewer
    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (876282..876629, complement)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Mms1p Neighboring gene Rho family GTPase RHO1 Neighboring gene phosphoadenylyl-sulfate reductase (thioredoxin) Neighboring gene mediator complex subunit NUT2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Assembly of the mitochondrial membrane system. MRP1 and MRP2, two yeast nuclear genes coding for mitochondrial ribosomal proteins. Myers AM, et al. J Biol Chem, 1987 Mar 5. PMID 3029111
    2. Incorporation of the yeast mitochondrial ribosomal protein Mrp2 into ribosomal subunits requires the mitochondrially encoded Var1 protein. Davis SC, et al. Mol Gen Genet, 1995 May 10. PMID 7770043
    3. Surveillance of 3' mRNA cleavage during transcription termination requires CF IB/Hrp1. Li J, et al. Nucleic Acids Res, 2023 Sep 8. PMID 37351636, Free PMC Article
    4. Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues. Saveanu C, et al. J Biol Chem, 2001 May 11. PMID 11278769
    5. Tag-mediated isolation of yeast mitochondrial ribosome and mass spectrometric identification of its new components. Gan X, et al. Eur J Biochem, 2002 Nov. PMID 12392552

    See all (29) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial translation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of mitochondrial small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of mitochondrial small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial 37S ribosomal protein MRP2
    NP_015492.1
    • Mitochondrial ribosomal protein of the small subunit

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      876282..876629 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184263.1 → NP_015492.1  TPA: mitochondrial 37S ribosomal protein MRP2 [Saccharomyces cerevisiae S288C]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W4G7, P10663
      UniProtKB/TrEMBL
      A6ZX42, B3LKC7, C7GP49, C8ZJJ2, G2WPX9, N1NWJ9
      Conserved Domains (1) summary
      pfam00253
      Location:61 → 112
      Ribosomal_S14; Ribosomal protein S14p/S29e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P10663.1

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