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    uncharacterized protein [ Saccharomyces cerevisiae S288C ]

    Gene ID: 855885, updated on 9-Dec-2024

    Summary

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    Official Full Name
    uncharacterized protein
    Primary source
    SGD:S000006137
    Locus tag
    YPL216W
    See related
    AllianceGenome:SGD:S000006137; FungiDB:YPL216W; VEuPathDB:YPL216W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to be involved in subtelomeric heterochromatin formation. Predicted to be located in chromatin and chromosome, telomeric region. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    Location:
    chromosome: XVI
    Exon count:
    1
    Sequence:
    Chromosome: XVI; NC_001148.4 (143821..147129)

    Chromosome XVI - NC_001148.4Genomic Context describing neighboring genes Neighboring gene Arf family GTPase SAR1 Neighboring gene GTPase BMS1 Neighboring gene Cbp3p Neighboring gene bifunctional hydroxyethylthiazole kinase/thiamine-phosphate diphosphorylase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001148.4

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comprehensive characterization of the Hsp70 interactome reveals novel client proteins and interactions mediated by posttranslational modifications. Nitika, et al. PLoS Biol, 2022 Oct. PMID 36269765, Free PMC Article
    2. Functional profiling of the Saccharomyces cerevisiae genome. Giaever G, et al. Nature, 2002 Jul 25. PMID 12140549
    3. Coiled-coil networking shapes cell molecular machinery. Wang Y, et al. Mol Biol Cell, 2012 Oct. PMID 22875988, Free PMC Article
    4. Cmr1/WDR76 defines a nuclear genotoxic stress body linking genome integrity and protein quality control. Gallina I, et al. Nat Commun, 2015 Mar 30. PMID 25817432, Free PMC Article
    5. The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI. Bussey H, et al. Nature, 1997 May 29. PMID 9169875

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in chromatin organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in subtelomeric heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in chromatin IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in chromosome, telomeric region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    NP_015108.1
    • hypothetical protein; not an essential gene; YPL216W has a paralog, ITC1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001148.4 Reference assembly

      Range
      143821..147129
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001184030.1 → NP_015108.1  TPA: uncharacterized protein YPL216W [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_015108.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W3F4, Q08964
      UniProtKB/TrEMBL
      C7GN43
      Conserved Domains (5) summary
      smart00571
      Location:375 → 435
      DDT; domain in different transcription and chromosome remodeling factors
      pfam10537
      Location:26 → 124
      WAC_Acf1_DNA_bd; ATP-utilizing chromatin assembly and remodelling N-terminal
      pfam15612
      Location:626 → 667
      WHIM1; WSTF, HB1, Itc1p, MBD9 motif 1
      pfam15613
      Location:750 → 793
      WHIM2; WSTF, HB1, Itc1p, MBD9 motif 2
      pfam15614
      Location:885 → 923
      WHIM3; WSTF, HB1, Itc1p, MBD9 motif 3
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08964.1

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