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    BUD21 Bud21p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854245, updated on 9-Dec-2024

    Summary

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    Official Symbol
    BUD21
    Official Full Name
    Bud21p
    Primary source
    SGD:S000005604
    Locus tag
    YOR078W
    See related
    AllianceGenome:SGD:S000005604; FungiDB:YOR078W; VEuPathDB:YOR078W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    UTP16; YOR29-29
    Summary
    Enables U3 snoRNA binding activity. Involved in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in nucleolus. Part of small-subunit processome. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See BUD21 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (472725..473369)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Ski7p Neighboring gene Rts2p Neighboring gene Mn(2+) transporter ATX2 Neighboring gene DNA-binding SCF ubiquitin ligase subunit DIA2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001147.6

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Chemical and Synthetic Genetic Array Analysis Identifies Genes that Suppress Xylose Utilization and Fermentation in Saccharomyces cerevisiae. Usher J, et al. G3 (Bethesda), 2011 Sep. PMID 22384336, Free PMC Article
    2. Deletion of a subgroup of ribosome-related genes minimizes hypoxia-induced changes and confers hypoxia tolerance. Shah AN, et al. Physiol Genomics, 2011 Jul 27. PMID 21586670, Free PMC Article
    3. The size of the nucleus increases as yeast cells grow. Jorgensen P, et al. Mol Biol Cell, 2007 Sep. PMID 17596521, Free PMC Article
    4. The small subunit processome is required for cell cycle progression at G1. Bernstein KA, et al. Mol Biol Cell, 2004 Nov. PMID 15356263, Free PMC Article
    5. RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components. Gallagher JE, et al. Genes Dev, 2004 Oct 15. PMID 15489292, Free PMC Article

    See all (83) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables U3 snoRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables snoRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of 90S preribosome HDA PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of small-subunit processome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Bud21p
    NP_014721.1
    • Component of small ribosomal subunit (SSU) processome; interacts with the U3 snoRNA (Snr17a/b); involved in rRNA processing and maturation; required post-transcriptionally for efficient retrotransposition; absence results in decreased Ty1 Gag:GFP protein levels; originally isolated as bud-site selection mutant that displays a random budding pattern; ortholog of human NOL7

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      472725..473369
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183497.1 → NP_014721.1  TPA: Bud21p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014721.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W2E1, O00033, Q08492
      UniProtKB/TrEMBL
      B3LJC7, B5VRX4, C7GT37, C8ZI40, G2WMV6, N1P317
      Conserved Domains (1) summary
      pfam08297
      Location:111 → 208
      U3_snoRNA_assoc; U3 snoRNA associated
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08492.1

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