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    SNR42 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 9164915, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SNR42
    Primary source
    SGD:S000006502
    Locus tag
    YNCK0020C
    See related
    AllianceGenome:SGD:S000006502
    Gene type
    ncRNA
    RNA name
    snoRNA
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables rRNA pseudouridylation guide activity. Involved in rRNA pseudouridine synthesis. Part of box H/ACA snoRNP complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See SNR42 in Genome Data Viewer
    Location:
    chromosome: XI
    Exon count:
    1
    Sequence:
    Chromosome: XI; NC_001143.9 (559016..559366, complement)

    Chromosome XI - NC_001143.9Genomic Context describing neighboring genes Neighboring gene Utp30p Neighboring gene mannosyltransferase KTR2 Neighboring gene transcription factor TFIIE subunit TFA2 Neighboring gene rRNA-processing protein LAS1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001143.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cbf5p, a potential pseudouridine synthase, and Nhp2p, a putative RNA-binding protein, are present together with Gar1p in all H BOX/ACA-motif snoRNPs and constitute a common bipartite structure. Watkins NJ, et al. RNA, 1998 Dec. PMID 9848653, Free PMC Article
    2. Structure of H/ACA RNP protein Nhp2p reveals cis/trans isomerization of a conserved proline at the RNA and Nop10 binding interface. Koo BK, et al. J Mol Biol, 2011 Sep 2. PMID 21708174, Free PMC Article
    3. Optimization of ribosome structure and function by rRNA base modification. Baxter-Roshek JL, et al. PLoS One, 2007 Jan 24. PMID 17245450, Free PMC Article
    4. The box H + ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase. Lafontaine DL, et al. Genes Dev, 1998 Feb 15. PMID 9472021, Free PMC Article
    5. The DEAD-box protein Dbp6 is an ATPase and RNA annealase interacting with the peptidyl transferase center (PTC) of the ribosome. Khreiss A, et al. Nucleic Acids Res, 2023 Jan 25. PMID 36610750, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    • H/ACA box small nucleolar RNA (snoRNA); guides pseudouridylation of large subunit (LSU) rRNA at position U2975

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables rRNA pseudouridylation guide activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in rRNA pseudouridine synthesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of box H/ACA snoRNP complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    located_in nucleolus IC
    Inferred by Curator
    more info
    		 PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001143.9 Reference assembly

      Range
      559016..559366 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. NR_132203.1 RNA Sequence

      Status: REVIEWED

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