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    ZNF384 zinc finger protein 384 [ Homo sapiens (human) ]

    Gene ID: 171017, updated on 10-Dec-2024

    Summary

    Official Symbol
    ZNF384provided by HGNC
    Official Full Name
    zinc finger protein 384provided by HGNC
    Primary source
    HGNC:HGNC:11955
    See related
    Ensembl:ENSG00000126746 MIM:609951; AllianceGenome:HGNC:11955
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NP; CIZ; NMP4; CAGH1; ERDA2; TNRC1; CAGH1A
    Summary
    This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011]
    Expression
    Ubiquitous expression in bone marrow (RPKM 12.2), testis (RPKM 12.0) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ZNF384 in Genome Data Viewer
    Location:
    12p13.31
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (6666477..6689572, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (6676834..6699927, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (6775643..6798738, complement)

    Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5872 Neighboring gene acrosin binding protein Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:6756019-6756532 Neighboring gene MPRA-validated peak1551 silencer Neighboring gene inhibitor of growth family member 4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5874 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr12:6798393-6799019 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5875 Neighboring gene PILR alpha associated neural protein Neighboring gene H3K4me1 hESC enhancer GRCh37_chr12:6808761-6809262 Neighboring gene RNA, U6 small nuclear 781, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ59043

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables sequence-specific double-stranded DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    zinc finger protein 384
    Names
    CAG repeat protein 1
    Cas-interacting zinc finger protein
    expanded repeat domain, CAG/CTG 2
    nuclear matrix transcription factor 4
    trinucleotide repeat-containing gene 1 protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039920.3NP_001035009.1  zinc finger protein 384 isoform c

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS31732.1
      UniProtKB/Swiss-Prot
      Q8TF68
      Related
      ENSP00000348018.4, ENST00000355772.8
      Conserved Domains (2) summary
      COG5048
      Location:153339
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:203223
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. NM_001135734.3NP_001129206.1  zinc finger protein 384 isoform d

      See identical proteins and their annotated locations for NP_001129206.1

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS44817.1
      UniProtKB/Swiss-Prot
      O15407, Q7Z722, Q8N938, Q8TF68
      UniProtKB/TrEMBL
      A0AA34QVS9
      Related
      ENSP00000380019.3, ENST00000396801.7
      Conserved Domains (2) summary
      COG5048
      Location:208408
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:319339
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. NM_001385739.1NP_001372668.1  zinc finger protein 384 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
    4. NM_001385740.1NP_001372669.1  zinc finger protein 384 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
    5. NM_001385741.1NP_001372670.1  zinc finger protein 384 isoform b

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:192378
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:242262
      ZF_C2H2; C2H2 Zn finger [structural motif]
    6. NM_001385742.1NP_001372671.1  zinc finger protein 384 isoform b

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:192378
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:242262
      ZF_C2H2; C2H2 Zn finger [structural motif]
    7. NM_001385743.1NP_001372672.1  zinc finger protein 384 isoform e

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS91645.1
      UniProtKB/TrEMBL
      A0A804HJE2, A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:284486
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:350370
      ZF_C2H2; C2H2 Zn finger [structural motif]
    8. NM_001385744.1NP_001372673.1  zinc finger protein 384 isoform e

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS91645.1
      UniProtKB/TrEMBL
      A0A804HJE2, A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:284486
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:350370
      ZF_C2H2; C2H2 Zn finger [structural motif]
    9. NM_001385745.1NP_001372674.1  zinc finger protein 384 isoform e

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS91645.1
      UniProtKB/TrEMBL
      A0A804HJE2, A0AA34QVS9
      Related
      ENSP00000507462.1, ENST00000683879.1
      Conserved Domains (2) summary
      COG5048
      Location:284486
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:350370
      ZF_C2H2; C2H2 Zn finger [structural motif]
    10. NM_001385746.1NP_001372675.1  zinc finger protein 384 isoform e

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS91645.1
      UniProtKB/TrEMBL
      A0A804HJE2, A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:284486
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:350370
      ZF_C2H2; C2H2 Zn finger [structural motif]
    11. NM_001385747.1NP_001372676.1  zinc finger protein 384 isoform e

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS91645.1
      UniProtKB/TrEMBL
      A0A804HJE2, A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:284486
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:350370
      ZF_C2H2; C2H2 Zn finger [structural motif]
    12. NM_001385748.1NP_001372677.1  zinc finger protein 384 isoform f

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:268470
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:334354
      ZF_C2H2; C2H2 Zn finger [structural motif]
    13. NM_001385749.1NP_001372678.1  zinc finger protein 384 isoform f

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:268470
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:334354
      ZF_C2H2; C2H2 Zn finger [structural motif]
    14. NM_001385750.1NP_001372679.1  zinc finger protein 384 isoform d

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS44817.1
      UniProtKB/Swiss-Prot
      O15407, Q7Z722, Q8N938, Q8TF68
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208408
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:319339
      ZF_C2H2; C2H2 Zn finger [structural motif]
    15. NM_001385751.1NP_001372680.1  zinc finger protein 384 isoform d

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS44817.1
      UniProtKB/Swiss-Prot
      O15407, Q7Z722, Q8N938, Q8TF68
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208408
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:319339
      ZF_C2H2; C2H2 Zn finger [structural motif]
    16. NM_001385752.1NP_001372681.1  zinc finger protein 384 isoform d

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS44817.1
      UniProtKB/Swiss-Prot
      O15407, Q7Z722, Q8N938, Q8TF68
      UniProtKB/TrEMBL
      A0AA34QVS9
      Related
      ENSP00000354592.3, ENST00000361959.7
      Conserved Domains (2) summary
      COG5048
      Location:208408
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:319339
      ZF_C2H2; C2H2 Zn finger [structural motif]
    17. NM_001385753.1NP_001372682.1  zinc finger protein 384 isoform d

      Status: REVIEWED

      Source sequence(s)
      AC125494, KF455592
      Consensus CDS
      CCDS44817.1
      UniProtKB/Swiss-Prot
      O15407, Q7Z722, Q8N938, Q8TF68
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208408
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:319339
      ZF_C2H2; C2H2 Zn finger [structural motif]
    18. NM_001385754.1NP_001372683.1  zinc finger protein 384 isoform d

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS44817.1
      UniProtKB/Swiss-Prot
      O15407, Q7Z722, Q8N938, Q8TF68
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208408
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:319339
      ZF_C2H2; C2H2 Zn finger [structural motif]
    19. NM_001385755.1NP_001372684.1  zinc finger protein 384 isoform d

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS44817.1
      UniProtKB/Swiss-Prot
      O15407, Q7Z722, Q8N938, Q8TF68
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208408
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:319339
      ZF_C2H2; C2H2 Zn finger [structural motif]
    20. NM_001385756.1NP_001372685.1  zinc finger protein 384 isoform d

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS44817.1
      UniProtKB/Swiss-Prot
      O15407, Q7Z722, Q8N938, Q8TF68
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208408
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:319339
      ZF_C2H2; C2H2 Zn finger [structural motif]
    21. NM_001385757.1NP_001372686.1  zinc finger protein 384 isoform d

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS44817.1
      UniProtKB/Swiss-Prot
      O15407, Q7Z722, Q8N938, Q8TF68
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208408
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:319339
      ZF_C2H2; C2H2 Zn finger [structural motif]
    22. NM_001385758.1NP_001372687.1  zinc finger protein 384 isoform g

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:192392
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:303323
      ZF_C2H2; C2H2 Zn finger [structural motif]
    23. NM_001385759.1NP_001372688.1  zinc finger protein 384 isoform g

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:192392
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:303323
      ZF_C2H2; C2H2 Zn finger [structural motif]
    24. NM_001385760.1NP_001372689.1  zinc finger protein 384 isoform g

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:192392
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:303323
      ZF_C2H2; C2H2 Zn finger [structural motif]
    25. NM_001385761.1NP_001372690.1  zinc finger protein 384 isoform g

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:192392
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:303323
      ZF_C2H2; C2H2 Zn finger [structural motif]
    26. NM_001385762.1NP_001372691.1  zinc finger protein 384 isoform h

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:229431
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:295315
      ZF_C2H2; C2H2 Zn finger [structural motif]
    27. NM_001385763.1NP_001372692.1  zinc finger protein 384 isoform i

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (4) summary
      COG5048
      Location:284425
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:289309
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:287309
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:329356
      zf-H2C2_2; Zinc-finger double domain
    28. NM_001385764.1NP_001372693.1  zinc finger protein 384 isoform i

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (4) summary
      COG5048
      Location:284425
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:289309
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:287309
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:329356
      zf-H2C2_2; Zinc-finger double domain
    29. NM_001385765.1NP_001372694.1  zinc finger protein 384 isoform i

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (4) summary
      COG5048
      Location:284425
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:289309
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:287309
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:329356
      zf-H2C2_2; Zinc-finger double domain
    30. NM_001385766.1NP_001372695.1  zinc finger protein 384 isoform i

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (4) summary
      COG5048
      Location:284425
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:289309
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:287309
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:329356
      zf-H2C2_2; Zinc-finger double domain
    31. NM_001385767.1NP_001372696.1  zinc finger protein 384 isoform i

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (4) summary
      COG5048
      Location:284425
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:289309
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:287309
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:329356
      zf-H2C2_2; Zinc-finger double domain
    32. NM_001385768.1NP_001372697.1  zinc finger protein 384 isoform j

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (4) summary
      COG5048
      Location:268409
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:273293
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:271293
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:313340
      zf-H2C2_2; Zinc-finger double domain
    33. NM_001385769.1NP_001372698.1  zinc finger protein 384 isoform j

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (4) summary
      COG5048
      Location:268409
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:273293
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:271293
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:313340
      zf-H2C2_2; Zinc-finger double domain
    34. NM_001385770.1NP_001372699.1  zinc finger protein 384 isoform j

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (4) summary
      COG5048
      Location:268409
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:273293
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:271293
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:313340
      zf-H2C2_2; Zinc-finger double domain
    35. NM_001385771.1NP_001372700.1  zinc finger protein 384 isoform k

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (3) summary
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:256278
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:359386
      zf-H2C2_2; Zinc-finger double domain
    36. NM_001385772.1NP_001372701.1  zinc finger protein 384 isoform l

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:153353
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:264284
      ZF_C2H2; C2H2 Zn finger [structural motif]
    37. NM_001385773.1NP_001372702.1  zinc finger protein 384 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
    38. NM_001385774.1NP_001372703.1  zinc finger protein 384 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
    39. NM_001385775.1NP_001372704.1  zinc finger protein 384 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
    40. NM_001385776.1NP_001372705.1  zinc finger protein 384 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
    41. NM_001385777.1NP_001372706.1  zinc finger protein 384 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
    42. NM_001385778.1NP_001372707.1  zinc finger protein 384 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
    43. NM_001385779.1NP_001372708.1  zinc finger protein 384 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
    44. NM_001385780.1NP_001372709.1  zinc finger protein 384 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
    45. NM_001385781.1NP_001372710.1  zinc finger protein 384 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
    46. NM_001385782.1NP_001372711.1  zinc finger protein 384 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
    47. NM_001385783.1NP_001372712.1  zinc finger protein 384 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
    48. NM_001385784.1NP_001372713.1  zinc finger protein 384 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
    49. NM_001385785.1NP_001372714.1  zinc finger protein 384 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
    50. NM_001385786.1NP_001372715.1  zinc finger protein 384 isoform a

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]
    51. NM_001385787.1NP_001372716.1  zinc finger protein 384 isoform b

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:192378
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:242262
      ZF_C2H2; C2H2 Zn finger [structural motif]
    52. NM_001385788.1NP_001372717.1  zinc finger protein 384 isoform b

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:192378
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:242262
      ZF_C2H2; C2H2 Zn finger [structural motif]
    53. NM_001385789.1NP_001372718.1  zinc finger protein 384 isoform b

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:192378
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:242262
      ZF_C2H2; C2H2 Zn finger [structural motif]
    54. NM_001385790.1NP_001372719.1  zinc finger protein 384 isoform b

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:192378
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:242262
      ZF_C2H2; C2H2 Zn finger [structural motif]
    55. NM_001385791.1NP_001372720.1  zinc finger protein 384 isoform b

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:192378
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:242262
      ZF_C2H2; C2H2 Zn finger [structural motif]
    56. NM_001385792.1NP_001372721.1  zinc finger protein 384 isoform b

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:192378
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:242262
      ZF_C2H2; C2H2 Zn finger [structural motif]
    57. NM_001385793.1NP_001372722.1  zinc finger protein 384 isoform b

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:192378
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:242262
      ZF_C2H2; C2H2 Zn finger [structural motif]
    58. NM_001385794.1NP_001372723.1  zinc finger protein 384 isoform b

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:192378
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:242262
      ZF_C2H2; C2H2 Zn finger [structural motif]
    59. NM_001385795.1NP_001372724.1  zinc finger protein 384 isoform b

      Status: REVIEWED

      Source sequence(s)
      AC125494
      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:192378
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:242262
      ZF_C2H2; C2H2 Zn finger [structural motif]
    60. NM_001385796.1NP_001372725.1  zinc finger protein 384 isoform m

      Status: REVIEWED

      Source sequence(s)
      AC125494, KF455592
      Conserved Domains (2) summary
      COG5048
      Location:169355
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:219239
      ZF_C2H2; C2H2 Zn finger [structural motif]
    61. NM_001385797.1NP_001372726.1  zinc finger protein 384 isoform n

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Conserved Domains (2) summary
      COG5048
      Location:160346
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:210230
      ZF_C2H2; C2H2 Zn finger [structural motif]
    62. NM_001385798.1NP_001372727.1  zinc finger protein 384 isoform c

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS31732.1
      Conserved Domains (2) summary
      COG5048
      Location:153339
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:203223
      ZF_C2H2; C2H2 Zn finger [structural motif]
    63. NM_001385799.1NP_001372728.1  zinc finger protein 384 isoform c

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS31732.1
      Conserved Domains (2) summary
      COG5048
      Location:153339
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:203223
      ZF_C2H2; C2H2 Zn finger [structural motif]
    64. NM_001385800.1NP_001372729.1  zinc finger protein 384 isoform c

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Consensus CDS
      CCDS31732.1
      Conserved Domains (2) summary
      COG5048
      Location:153339
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:203223
      ZF_C2H2; C2H2 Zn finger [structural motif]
    65. NM_001385801.1NP_001372730.1  zinc finger protein 384 isoform o

      Status: REVIEWED

      Source sequence(s)
      AC125494
      Conserved Domains (3) summary
      sd00017
      Location:242262
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:240262
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:282309
      zf-H2C2_2; Zinc-finger double domain
    66. NM_133476.5NP_597733.2  zinc finger protein 384 isoform a

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate in-frame exon in the central coding region, compared to variant 7, resulting in an isoform (a) that is shorter than isoform d.
      Source sequence(s)
      AK095734, AL047623, AV689743, BP363856, CA442809
      Consensus CDS
      CCDS8557.1
      UniProtKB/TrEMBL
      A0AA34QVS9
      Related
      ENSP00000321650.4, ENST00000319770.7
      Conserved Domains (2) summary
      COG5048
      Location:208394
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:258278
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RNA

    1. NR_169758.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC125494
    2. NR_169759.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC125494
    3. NR_169760.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC125494
    4. NR_169761.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC125494
    5. NR_169762.1 RNA Sequence

      Status: REVIEWED

      Source sequence(s)
      AC125494

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

      Range
      6666477..6689572 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047428472.1XP_047284428.1  zinc finger protein 384 isoform X5

      UniProtKB/TrEMBL
      A0AA34QVS9
    2. XM_011520922.1XP_011519224.1  zinc finger protein 384 isoform X2

      See identical proteins and their annotated locations for XP_011519224.1

      UniProtKB/TrEMBL
      A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:268470
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:334354
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. XM_047428471.1XP_047284427.1  zinc finger protein 384 isoform X4

      UniProtKB/TrEMBL
      A0AA34QVS9
    4. XM_047428467.1XP_047284423.1  zinc finger protein 384 isoform X1

      UniProtKB/TrEMBL
      A0A804HJE2, A0AA34QVS9
    5. XM_047428473.1XP_047284429.1  zinc finger protein 384 isoform X5

      UniProtKB/TrEMBL
      A0AA34QVS9
    6. XM_047428470.1XP_047284426.1  zinc finger protein 384 isoform X4

      UniProtKB/TrEMBL
      A0AA34QVS9
    7. XM_011520919.3XP_011519221.1  zinc finger protein 384 isoform X1

      See identical proteins and their annotated locations for XP_011519221.1

      UniProtKB/TrEMBL
      A0A804HJE2, A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:284486
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:350370
      ZF_C2H2; C2H2 Zn finger [structural motif]
    8. XM_047428474.1XP_047284430.1  zinc finger protein 384 isoform X6

      UniProtKB/TrEMBL
      A0AA34QVS9
    9. XM_047428468.1XP_047284424.1  zinc finger protein 384 isoform X3

      UniProtKB/TrEMBL
      A0AA34QVS9
    10. XM_047428469.1XP_047284425.1  zinc finger protein 384 isoform X4

      UniProtKB/TrEMBL
      A0AA34QVS9
    11. XM_011520917.3XP_011519219.1  zinc finger protein 384 isoform X1

      See identical proteins and their annotated locations for XP_011519219.1

      UniProtKB/TrEMBL
      A0A804HJE2, A0AA34QVS9
      Conserved Domains (2) summary
      COG5048
      Location:284486
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:350370
      ZF_C2H2; C2H2 Zn finger [structural motif]
    12. XM_006718969.4XP_006719032.1  zinc finger protein 384 isoform X7

      See identical proteins and their annotated locations for XP_006719032.1

      Conserved Domains (3) summary
      COG5048
      Location:22177
      COG5048; FOG: Zn-finger [General function prediction only]
      COG5189
      Location:138190
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:88108
      ZF_C2H2; C2H2 Zn finger [structural motif]

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060936.1 Alternate T2T-CHM13v2.0

      Range
      6676834..6699927 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054371348.1XP_054227323.1  zinc finger protein 384 isoform X5

      UniProtKB/TrEMBL
      A0AA34QVS9
    2. XM_054371343.1XP_054227318.1  zinc finger protein 384 isoform X2

      UniProtKB/TrEMBL
      A0AA34QVS9
    3. XM_054371347.1XP_054227322.1  zinc finger protein 384 isoform X4

      UniProtKB/TrEMBL
      A0AA34QVS9
    4. XM_054371342.1XP_054227317.1  zinc finger protein 384 isoform X1

      UniProtKB/TrEMBL
      A0AA34QVS9
    5. XM_054371349.1XP_054227324.1  zinc finger protein 384 isoform X5

      UniProtKB/TrEMBL
      A0AA34QVS9
    6. XM_054371346.1XP_054227321.1  zinc finger protein 384 isoform X4

      UniProtKB/TrEMBL
      A0AA34QVS9
    7. XM_054371340.1XP_054227315.1  zinc finger protein 384 isoform X1

      UniProtKB/TrEMBL
      A0AA34QVS9
    8. XM_054371350.1XP_054227325.1  zinc finger protein 384 isoform X6

    9. XM_054371344.1XP_054227319.1  zinc finger protein 384 isoform X3

      UniProtKB/TrEMBL
      A0AA34QVS9
    10. XM_054371345.1XP_054227320.1  zinc finger protein 384 isoform X4

      UniProtKB/TrEMBL
      A0AA34QVS9
    11. XM_054371341.1XP_054227316.1  zinc finger protein 384 isoform X1

      UniProtKB/TrEMBL
      A0AA34QVS9
    12. XM_054371351.1XP_054227326.1  zinc finger protein 384 isoform X7

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001039916.1: Suppressed sequence

      Description
      NM_001039916.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.
    2. NM_001039917.1: Suppressed sequence

      Description
      NM_001039917.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.
    3. NM_001039918.1: Suppressed sequence

      Description
      NM_001039918.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
    4. NM_001039919.1: Suppressed sequence

      Description
      NM_001039919.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.