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    MIR4697 microRNA 4697 [ Homo sapiens (human) ]

    Gene ID: 100616119, updated on 10-Dec-2024

    Summary

    Official Symbol
    MIR4697provided by HGNC
    Official Full Name
    microRNA 4697provided by HGNC
    Primary source
    HGNC:HGNC:41570
    See related
    Ensembl:ENSG00000284020 miRBase:MI0017330; AllianceGenome:HGNC:41570
    Gene type
    ncRNA
    RefSeq status
    PROVISIONAL
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Summary
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
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    Genomic context

    See MIR4697 in Genome Data Viewer
    Location:
    11q25
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (133898504..133898581, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (133940798..133940875, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (133768399..133768476, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133712096-133712638 Neighboring gene spermatogenesis associated 19 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr11:133724195-133725394 Neighboring gene calponin 2 pseudogene Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133764343-133765238 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133765239-133766134 Neighboring gene immunoglobulin superfamily member 9B Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4088 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133800389-133801061 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133804210-133804968 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133804969-133805727 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133809401-133810123 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133810124-133810845 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133814904-133815632 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133816362-133817090 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 5767 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133821059-133821802 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133821803-133822546 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 4089 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133863530-133864030 Neighboring gene long intergenic non-protein coding RNA 2730 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133890717-133891220 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133894031-133894833 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr11:133896267-133896838 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr11:133896839-133897409 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133901031-133901530 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr11:133902231-133902958 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133902959-133903686 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr11:133906753-133907724 Neighboring gene long intergenic non-protein coding RNA 2731

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    BioGRID CRISPR Screen Phenotypes (6 hits/95 screens)

    EBI GWAS Catalog

    Description
    Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease.
    EBI GWAS Catalog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    RNA

    1. NR_039846.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)
      AP001979
      Related
      ENST00000582977.1

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

      Range
      133898504..133898581 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060935.1 Alternate T2T-CHM13v2.0

      Range
      133940798..133940875 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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